Centre d'Etudes en Psychopathologie et Psychologie de la Santé (EA 7411), University of Toulouse Jean Jaurès, Toulouse, France.
Department of Neurosurgery, Angers University Hospital, Angers, France.
Psychol Health Med. 2023 Dec;28(10):2860-2871. doi: 10.1080/13548506.2023.2190596. Epub 2023 Mar 15.
The present study focused on adult primary brain tumor (PBT) survivors' caregivers. The main objective was to study associations between PBT survivors' health-related quality of life (HRQOL), their behavioral executive functions (EF) and their caregivers' HRQOL. Forty PBT survivors of PBT and 37 caregivers (mostly patient's spouses 81.08%; = 30) participated in the study. PBT survivors completed a cancer related Quality of Life (QOL) questionnaire. Caregivers completed informant rated HRQOL and behavioral EF reports relating to PBT survivors and a self-rated HRQOL questionnaire relating to themselves. Correlational and multiple regression analyses were conducted. No associations were found between caregivers' physical HRQOL and PBT survivors' HRQOL nor behavioral EF. Analyses yielded several significant correlations between caregivers' mental HRQOL and variables pertaining to PBT survivors' HRQOL and behavioral EF. Multiple regression analyses showed that caregivers' mental HRQOL is predicted by PBT survivors' mental HRQOL, global cancer-related QOL scores and global behavioral EF scores. This study provides evidence suggesting that during the survivorship phase, at an average of 3.67 (SD = 2.31) years following treatment for a PBT, caregivers mental HRQOL is linked to PBT survivors' long-term effects. These findings shed some light regarding post-cancer care for both PBT survivors and their caregivers.
本研究关注的是成人原发性脑肿瘤（PBT）幸存者的照顾者。主要目的是研究 PBT 幸存者的健康相关生活质量（HRQOL）、他们的行为执行功能（EF）与其照顾者的 HRQOL 之间的关联。40 名 PBT 幸存者和 37 名照顾者（大多数是患者的配偶，占 81.08%； = 30）参与了这项研究。PBT 幸存者完成了一份癌症相关生活质量（QOL）问卷。照顾者完成了与 PBT 幸存者有关的照顾者自评 HRQOL 和行为 EF 报告，以及与自己有关的自评 HRQOL 问卷。进行了相关和多元回归分析。未发现照顾者的身体 HRQOL 与 PBT 幸存者的 HRQOL 或行为 EF 之间存在关联。分析得出了几个照顾者的心理 HRQOL 与 PBT 幸存者的 HRQOL 和行为 EF 相关变量之间的显著相关性。多元回归分析表明，照顾者的心理 HRQOL 由 PBT 幸存者的心理 HRQOL、全球癌症相关 QOL 评分和全球行为 EF 评分预测。这项研究提供了证据表明，在治疗 PBT 后的平均 3.67 年（SD = 2.31）的生存阶段，照顾者的心理 HRQOL 与 PBT 幸存者的长期影响有关。这些发现为 PBT 幸存者及其照顾者的癌症后护理提供了一些启示。
