Cantisano Nicole, Menei Philippe, Roualdes Vincent, Seizeur Romuald, Allain Philippe, Le Gall Didier, Roy Arnaud, Dinomais Mickaël, Besnard Jérémy
Centre d'Etudes en Psychopathologie et Psychologie de la Santé (EA 7411), University of Toulouse Jean Jaurès, Toulouse, France.
Department of Neurosurgery, Angers University Hospital, Angers, France.
J Cancer Surviv. 2021 Oct;15(5):696-705. doi: 10.1007/s11764-020-00961-0. Epub 2020 Oct 26.
The main objective of this study was to provide further information concerning the validity of patient-reported executive function (EF) in survivors of primary brain tumor (PBT) compared with a report provided by each patient's caregiver.
Forty survivors of PBT, 40 non-cancer controls and their proxies completed an assessment of functional executive disorders (e.g., planning, inhibition, shifting, action initiation). Comparisons of self and informant EF reports were examined, for both patients and non-cancer controls. The extent of the concordance between patients' reports and their caregivers' reports was also determined.
PBT survivors and their caregivers reported more problems related to EF in contrast with the non-cancer comparison group (significant differences). There was a high level of agreement between patients' and caregivers' ratings within the patient group.
This study provides evidence suggesting that at an average of 3.67 (SD = 2.31) years following treatment for a PBT, EF difficulties are reported by patients and their caregivers. This study establishes a consistency between what is reported by survivors and what is reported by those who frequently interact with them. Further research investigating the link between these ratings and quality of life as well as other functions is encouraged.
This study's results demonstrate the importance of listening to PBT survivors' perception of EF difficulties. While not confirmed by neuropsychological evaluations, the functional executive challenges reported by these survivors' close relatives reflect what PBT survivors themselves report. Specialists should pay close attention to these difficulties to guarantee optimal post-cancer care.
本研究的主要目的是提供更多信息，以比较原发性脑肿瘤（PBT）幸存者报告的执行功能（EF）与每位患者照顾者报告的执行功能的有效性。
40名PBT幸存者、40名非癌症对照者及其代理人完成了功能执行障碍评估（如计划、抑制、转换、行动启动）。对患者和非癌症对照者的自我报告和 informant EF报告进行了比较。还确定了患者报告与其照顾者报告之间的一致程度。
与非癌症对照组相比，PBT幸存者及其照顾者报告了更多与EF相关的问题（存在显著差异）。患者组内患者和照顾者的评分之间存在高度一致性。
本研究提供的证据表明，在PBT治疗后平均3.67年（标准差=2.31），患者及其照顾者报告了EF困难。本研究确定了幸存者报告的内容与经常与他们互动的人报告的内容之间的一致性。鼓励进一步研究调查这些评分与生活质量以及其他功能之间的联系。
本研究结果表明倾听PBT幸存者对EF困难的看法很重要。虽然未经神经心理学评估证实，但这些幸存者的近亲报告的功能执行挑战反映了PBT幸存者自己的报告。专家应密切关注这些困难，以确保最佳的癌症后护理。
