Center for Congenital Heart Disease, Department of Cardiac Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Clinic for Cardiovascular Surgery, University Heart Centre Freiburg-Bad, Krozingen, Germany.
Eur J Cardiothorac Surg. 2023 May 2;63(5). doi: 10.1093/ejcts/ezad075.
This study aims to describe the outcomes of surgical correction for anomalous aortic origin of coronary artery (AAOCA) with regard to symptom relief.
We performed a retrospective multicentre study including surgical patients who underwent correction for AAOCA between 2009 and 2022. Patients who underwent concomitant cardiac procedures were also included. However, to analyse symptom relief, we only assessed the subgroup of symptomatic patients who underwent isolated correction for AAOCA.
A total of 71 consecutive patients (median age 55, range 12-83) who underwent surgical correction for AAOCA were included in the study. Right-AAOCA was present in 56 patients (79%), left-AAOCA in 11 patients (15%) and single coronary ostium AAOCA in 4 patients (6%). Coronary unroofing was performed in 72% of the patients, coronary reimplantation in 28% and an additional neo-ostium patchplasty in 13% of the patients. In 39% of the patients, a concomitant cardiac procedure was performed. During follow-up, no cardiovascular-related death was observed. Three patients (4.2%) had a myocardial infarction and underwent postoperative coronary artery bypass grafting. Six patients (8.5%) needed postoperative temporary mechanical circulatory support. Among the 34 symptomatic patients who underwent isolated AAOCA correction, 70% were completely asymptomatic after surgery, 12% showed symptom improvement and no symptom improvement was observed in 18% of the patients (median follow-up 3.5 years, range 0.3-11.1).
Correction for AAOCA can be safely performed with or without concomitant cardiac procedures. Performing AAOCA correction leads to a significant improvement in symptoms for most patients.
本研究旨在描述手术矫正异常起源的冠状动脉(AAOCA)的结果,重点关注症状缓解情况。
我们进行了一项回顾性多中心研究,纳入了 2009 年至 2022 年期间接受 AAOCA 矫正手术的患者。同时也纳入了接受同期心脏手术的患者。然而,为了分析症状缓解情况,我们仅评估了接受单纯 AAOCA 矫正的有症状患者亚组。
本研究共纳入 71 例连续接受 AAOCA 手术矫正的患者(中位年龄 55 岁,范围 12-83 岁)。56 例(79%)为右冠状动脉起源异常,11 例(15%)为左冠状动脉起源异常,4 例(6%)为单一冠状动脉开口异常。72%的患者接受了冠状动脉开窗术,28%的患者接受了冠状动脉再植入术,13%的患者接受了额外的新开口补片成形术。39%的患者同时进行了心脏手术。随访期间,无心血管相关死亡。3 例(4.2%)患者发生心肌梗死,行术后冠状动脉旁路移植术。6 例(8.5%)患者需要术后临时机械循环支持。在 34 例接受单纯 AAOCA 矫正的有症状患者中,70%的患者术后完全无症状,12%的患者症状改善,18%的患者症状无改善(中位随访时间 3.5 年,范围 0.3-11.1 年)。
AAOCA 的矫正可以安全地在有或没有同期心脏手术的情况下进行。进行 AAOCA 矫正可显著改善大多数患者的症状。