Medical Oncology Unit, La Maddalena Clinic for Cancer, Palermo, and Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy.
Clinical Nutrition Service, ASP, Palermo, Italy.
Clin Ter. 2023 Mar-Apr;174(2):203-210. doi: 10.7417/CT.2023.2520.
Pancreatic cancer is associated to a high risk of malnutrition and neoplastic cachexia even at first diagnosis. Malnutrition is a negative prognostic factor for the outcome of surgery or medical oncology treatments. Despite the good awareness of the problem and the knowledge of the guidelines, the early recognition of malnutrition and its management are still uneven, mainly due to the lack of implementation of standardized and shared protocols and the shortage of dedicated clinical nutritionists and dieticians. An early and appropriate nutritional intervention is mandatory to improve the outcome of patients with pancreatic cancer at any stage of disease. The Mini Nutritional Assessment is useful tool to screen patients malnourished or at risk of malnutrition. The need for the establishment and implementation of an integrated hospital - territorial assistance as well as a home-delivered nutrition service is discussed.
胰腺癌在初诊时就与营养不良和肿瘤恶病质的高风险相关。营养不良是手术或肿瘤内科治疗结果的一个负面预后因素。尽管对这一问题有很好的认识和对指南的了解，但营养不良的早期识别和管理仍然参差不齐，主要是由于缺乏标准化和共享的方案以及缺乏专门的临床营养师和饮食学家。早期和适当的营养干预对于改善任何阶段的胰腺癌患者的预后是强制性的。微型营养评估是筛查营养不良或有营养不良风险患者的有用工具。讨论了建立和实施综合医院-地区援助以及家庭营养服务的必要性。
