Lazarus Jeffrey V, Wohl David A, Cascio Mario, Guaraldi Giovanni, Rockstroh Jürgen, Hodson Matthew, Richman Bruce, Brown Gina, Anderson Jane, Fuster-RuizdeApodaca Maria J
Barcelona Institute of Global Health (ISGlobal), Hospital Clínic, University of Barcelona, Barcelona, Spain.
City University of New York Graduate School of Public Health and Health Policy (CUNY SPH), New York, New York, USA.
HIV Med. 2023 Mar;24 Suppl 2:8-19. doi: 10.1111/hiv.13460.
In recent decades, the needs of people living with HIV have evolved as life expectancy has greatly improved. Now, a new definition of long-term success (LTS) is necessary to help address the multifaceted needs of all people living with HIV.
We conducted a two-phase research programme to delineate the range of experiences of people living with HIV. The insights garnered from these research phases were explored in a series of expert-led workshops, which led to the development and refinement of the LTS framework.
The insights generated from the research phases identified a series of themes that form a part of LTS. These themes were subsequently incorporated into the LTS framework, which includes five outcome pillars: sustained undetectable viral load, minimal impact of treatment and clinical monitoring, optimized health-related quality of life, lifelong integration of healthcare, and freedom from stigma and discrimination. A series of supporting statements were also developed by the expert panel to help in the achievement of each of the LTS pillars.
The LTS framework offers a comprehensive and person-centric approach that, if achieved, could help improve the long-term well-being of people living with HIV and support the LTS vision of 'every person living with HIV being able to live their best life'.
近几十年来，随着预期寿命大幅提高，艾滋病毒感染者的需求也发生了变化。现在，需要一个长期成功（LTS）的新定义来帮助满足所有艾滋病毒感染者的多方面需求。
我们开展了一个两阶段研究项目，以描绘艾滋病毒感染者的经历范围。在一系列由专家主导的研讨会上探讨了从这些研究阶段获得的见解，这促成了长期成功框架的制定和完善。
研究阶段产生的见解确定了一系列构成长期成功一部分的主题。这些主题随后被纳入长期成功框架，该框架包括五个成果支柱：持续病毒载量不可检测、治疗和临床监测的最小影响、优化的健康相关生活质量、医疗保健的终身整合以及免受耻辱和歧视。专家小组还制定了一系列支持性声明，以帮助实现长期成功的每个支柱。
长期成功框架提供了一种全面且以患者为中心的方法，如果得以实现，有助于改善艾滋病毒感染者的长期福祉，并支持“每个艾滋病毒感染者都能过上最好的生活”这一长期成功愿景。
