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猴痘在拉丁美洲免疫抑制患者中的晚期眼科表现。

Late ophthalmologic manifestations of monkeypox in a Latin American immunosuppressed patient.

机构信息

Visual Neurophysiology Laboratory, Department of Systems Biology, Physiology Unit, Faculty of Medicine and Health Sciences, Universidad de Alcalá, Madrid, Madrid, Spain.

Ophthalmologist, Department of Surgery, Ophthalmology Unit, Faculty of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia.

出版信息

Int J STD AIDS. 2023 Jun;34(7):491-493. doi: 10.1177/09564624231162180. Epub 2023 Mar 15.

DOI:10.1177/09564624231162180
PMID:36922742
Abstract

BACKGROUND

The re-emergence of Monkeypox (MPX) and its related ophthalmic disease represent a clinical challenge in the initial stages because of the presence of lesions like those caused by varicella zoster, syphilis, and other infections due to other poxviruses. Human Immunodeficiency Virus (HIV) infection and secondary immunodepression raise the risk of severe and prolonged disease.

PURPOSE

We present the case of a young immunosuppressed male patient with MPX, who presented with multiple skin lesions, also including risky ophthalmological manifestations due to extensive eyelid involvement.

CONCLUSIONS

We describe a novel form of late-onset conjunctivitis and eyelid lesions, without active extraocular disease, highlighting the heterogeneous behavior of the new clinical form of MPX, that exhibits a wide spectrum of lesions in different stages of evolution.

摘要

背景

猴痘(MPX)及其相关眼部疾病的再次出现给临床带来了挑战,因为存在类似水痘带状疱疹、梅毒和其他痘病毒引起的感染的病变。人类免疫缺陷病毒(HIV)感染和继发免疫抑制会增加严重和长期疾病的风险。

目的

我们报告了一例年轻免疫抑制男性 MPX 患者,他有多处皮肤损伤,由于广泛的眼睑受累,还伴有危险的眼部表现。

结论

我们描述了一种新型的迟发性结膜炎和眼睑病变,没有活动性眼外疾病,突出了新型 MPX 临床形式的异质性表现,其在不同的演变阶段表现出广泛的病变。

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引用本文的文献

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Spectrum of ophthalmic manifestations in monkeypox virus infection worldwide: Systematic review and meta-analysis.全球猴痘病毒感染的眼部表现谱:系统评价与荟萃分析
Heliyon. 2023 Jul 22;9(8):e18561. doi: 10.1016/j.heliyon.2023.e18561. eCollection 2023 Aug.