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自体富血小板纤维蛋白辅助成熟恒牙血运重建的临床观察。

Clinical observation of autologous platelet rich fibrin assisted revascularization of mature permanent teeth.

机构信息

Department of Endodontics, Stomatological Hospital of Xiamen Medical College, Huli District, No.1309, Lvling Road, Xiamen, 361008, Fujian, China.

Xiamen Key Laboratory of Stomatological Disease Diagnosis and Treatment, Fujian, 361008, China.

出版信息

Head Face Med. 2023 Mar 15;19(1):9. doi: 10.1186/s13005-023-00350-9.

DOI:10.1186/s13005-023-00350-9
PMID:36922821
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10015916/
Abstract

OBJECTIVE

To investigate the clinical observation of autologous platelet-rich fibrin (PRF) assisting the revascularization of mature permanent teeth.

METHODS

Twenty patients with mature permanent teeth were divided into experimental group and control group. The control group was treated with classic revascularization, and the experimental group was treated with PRF-assisted mature permanent tooth revascularization.

RESULTS

After treatment, the total effective rate of the experimental group (100.00%) was higher than that of the control group (50.00%); the thickness of the root canal wall of the experimental group was higher than that of the control group, and the crown root length was lower than that of the control group; The bite degree, chewing function, color, overall aesthetic score, and satisfaction rate of the patients were higher, and the difference was statistically significant (P < 0.05).

CONCLUSION

Autologous PRF assists in revascularization of mature permanent teeth, which can achieve ideal results, and promote pulp regeneration.

摘要

目的

探讨富血小板纤维蛋白(PRF)辅助成熟恒牙再血管化的临床观察。

方法

选择 20 例成熟恒牙患者分为实验组和对照组,对照组采用经典再血管化治疗,实验组采用 PRF 辅助成熟恒牙再血管化治疗。

结果

治疗后,实验组总有效率(100.00%)高于对照组(50.00%);实验组根管壁厚度高于对照组,冠根长度低于对照组;患者的咬合度、咀嚼功能、颜色、整体美观评分和满意度较高,差异有统计学意义(P < 0.05)。

结论

自体富血小板纤维蛋白辅助成熟恒牙再血管化,可获得理想的效果,促进牙髓再生。

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Clinical observation of autologous platelet rich fibrin assisted revascularization of mature permanent teeth.自体富血小板纤维蛋白辅助成熟恒牙血运重建的临床观察。
Head Face Med. 2023 Mar 15;19(1):9. doi: 10.1186/s13005-023-00350-9.
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本文引用的文献

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The feasibility of injectable PRF (I-PRF) for bone tissue engineering and its application in oral and maxillofacial reconstruction: From bench to chairside.注射用富血小板纤维蛋白(I-PRF)在骨组织工程中的可行性及其在口腔颌面重建中的应用:从实验室到临床。
Biomater Adv. 2022 Mar;134:112557. doi: 10.1016/j.msec.2021.112557. Epub 2021 Nov 24.
2
Platelet-Rich Fibrin Used in Regenerative Endodontics and Dentistry: Current Uses, Limitations, and Future Recommendations for Application.富血小板纤维蛋白在再生牙髓病学和牙科中的应用:当前用途、局限性及未来应用建议
Int J Dent. 2021 Dec 15;2021:4514598. doi: 10.1155/2021/4514598. eCollection 2021.
3
J Orthop. 2024 Feb 16;52:94-101. doi: 10.1016/j.jor.2024.02.009. eCollection 2024 Jun.
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Advancing Dentistry through Bioprinting: Personalization of Oral Tissues.通过生物打印推动牙科发展:口腔组织的个性化定制
J Funct Biomater. 2023 Oct 20;14(10):530. doi: 10.3390/jfb14100530.
Dentition and body condition: tooth wear as a correlate of weight loss in roe deer.
牙齿与身体状况:狍子牙齿磨损与体重减轻的关联
Front Zool. 2021 Sep 20;18(1):47. doi: 10.1186/s12983-021-00433-w.
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Functional Dental Pulp Regeneration: Basic Research and Clinical Translation.功能性牙髓再生:基础研究与临床转化。
Int J Mol Sci. 2021 Aug 20;22(16):8991. doi: 10.3390/ijms22168991.
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Clin Oral Investig. 2020 Dec;24(12):4373-4383. doi: 10.1007/s00784-020-03303-7. Epub 2020 May 7.
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Cureus. 2020 Jan 23;12(1):e6747. doi: 10.7759/cureus.6747.