胆囊收缩素相关肽刺激胰腺腺泡细胞中的钠/氢反向转运体导致细胞质碱化。
CCK-related peptides stimulation of the Na+/H+ antiport in pancreatic acinar cells leads to cytoplasmic alkalinisation.
作者信息
Bastie M J, Dufresne M, Delvaux M, Vaysse N, Ribet A
机构信息
U151 INSERM, CHU Rangueil, Toulouse, France.
出版信息
Gut. 1987;28 Suppl(Suppl):85-8. doi: 10.1136/gut.28.suppl.85.
Abstract
Caerulein, gastrin and pentagastrin stimulation of the Na+/H+ exchange leads to intracellular alkalinisation in pancreatic acinar cells. Activation of protein kinase-C is the more probable mechanism involved in the effect of caerulein.
摘要
蛙皮素、胃泌素和五肽胃泌素对钠氢交换的刺激会导致胰腺腺泡细胞内碱化。蛋白激酶-C的激活更可能是蛙皮素发挥作用的机制。
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本文引用的文献
1
Na+/H+ antiport in Swiss 3T3 cells: mitogenic stimulation leads to cytoplasmic alkalinization.瑞士3T3细胞中的钠/氢逆向转运体：有丝分裂刺激导致细胞质碱化。
Proc Natl Acad Sci U S A. 1982 Dec;79(24):7778-82. doi: 10.1073/pnas.79.24.7778.
2
Metabolic regulation via intracellular pH.通过细胞内pH值进行的代谢调节
Am J Physiol. 1984 Apr;246(4 Pt 2):R409-38. doi: 10.1152/ajpregu.1984.246.4.R409.
3
Growth factor action and intracellular pH regulation in fibroblasts. Evidence for a major role of the Na+/H+ antiport.成纤维细胞中的生长因子作用与细胞内pH调节。钠/氢反向转运体起主要作用的证据。
J Biol Chem. 1984 May 10;259(9):5809-15.
4
Effects of growth factors on intracellular pH regulation.生长因子对细胞内pH调节的影响。
Annu Rev Physiol. 1986;48:363-76. doi: 10.1146/annurev.ph.48.030186.002051.
5
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FEBS Lett. 1985 Jul 22;187(1):126-30. doi: 10.1016/0014-5793(85)81227-8.
6
Coupled Na+-H+ exchange in isolated acinar cells from rat exocrine pancreas.大鼠外分泌胰腺分离腺泡细胞中的耦合钠氢交换
Am J Physiol. 1985 Jul;249(1 Pt 1):G125-36. doi: 10.1152/ajpgi.1985.249.1.G125.
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