Genetic Mechanisms Behind Severe Psychotic Reactions to Levetiracetam.
作者信息
Andrade Danielle M
机构信息
Neurology, University of Toronto Adult Genetic Epilepsy (AGE) Program, Toronto Western Hospital.
出版信息
Epilepsy Curr. 2022 Nov 29;23(1):29-31. doi: 10.1177/15357597221137409. eCollection 2023 Jan-Feb.
Abstract
摘要
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本文引用的文献
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A pharmacogenomic assessment of psychiatric adverse drug reactions to levetiracetam.左乙拉西坦致精神药物不良反应的药物基因组学评估。
Epilepsia. 2022 Jun;63(6):1563-1570. doi: 10.1111/epi.17228. Epub 2022 Apr 1.
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Polygenic burden in focal and generalized epilepsies.多基因负担在局灶性和全面性癫痫中的作用。
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A Screening Test for in a Large United States Patient Cohort Identifies Broader Risk of Carbamazepine-Induced Adverse Events.在美国一个大型患者队列中进行的一项筛查试验发现卡马西平诱导的不良事件风险范围更广。
Front Pharmacol. 2019 Mar 26;10:149. doi: 10.3389/fphar.2019.00149. eCollection 2019.
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Prediction Tools for Psychiatric Adverse Effects After Levetiracetam Prescription.左乙拉西坦处方后精神不良事件预测工具。
JAMA Neurol. 2019 Apr 1;76(4):440-446. doi: 10.1001/jamaneurol.2018.4561.
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Polygenic risk score for schizophrenia is more strongly associated with ancestry than with schizophrenia.精神分裂症的多基因风险评分与血统的关联比与精神分裂症的关联更强。
Psychiatr Genet. 2018 Oct;28(5):85-89. doi: 10.1097/YPG.0000000000000206.
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Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations.全基因组多基因疾病风险评分可识别出与单基因突变风险相当的个体。
Nat Genet. 2018 Sep;50(9):1219-1224. doi: 10.1038/s41588-018-0183-z. Epub 2018 Aug 13.
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Psychiatric and behavioral side effects of antiepileptic drugs in adults with epilepsy.抗癫痫药物在成年癫痫患者中的精神和行为副作用。
Epilepsy Behav. 2017 Nov;76:24-31. doi: 10.1016/j.yebeh.2017.08.039. Epub 2017 Sep 18.
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22q11.2 deletion syndrome lowers seizure threshold in adult patients without epilepsy.22q11.2 缺失综合征降低成年癫痫患者的癫痫发作阈值。
Epilepsia. 2017 Jun;58(6):1095-1101. doi: 10.1111/epi.13748. Epub 2017 Apr 27.
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Response to clozapine in a clinically identifiable subtype of schizophrenia.氯氮平对精神分裂症临床可识别亚型的反应。
Br J Psychiatry. 2015 Jun;206(6):484-91. doi: 10.1192/bjp.bp.114.151837. Epub 2015 Mar 5.
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Biological insights from 108 schizophrenia-associated genetic loci.108 个精神分裂症相关遗传位点的生物学见解。
Nature. 2014 Jul 24;511(7510):421-7. doi: 10.1038/nature13595. Epub 2014 Jul 22.
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