Marginalizing the genomic architecture to identify crosstalk across cancer and neurodegeneration.
作者信息
Sharma Amit, Wüllner Ullrich, Schmidt-Wolf Ingo G H, Maciaczyk Jarek
机构信息
Department of Neurosurgery, University Hospital of Bonn, Bonn, Germany.
Department of Neurology, University Hospital of Bonn, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
出版信息
Front Mol Neurosci. 2023 Feb 27;16:1155177. doi: 10.3389/fnmol.2023.1155177. eCollection 2023.
Abstract
摘要
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3
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