Wynne H, Bateman D N, Hassanyeh F, Rawlins M D, Woodhouse K W
Department of Clinical Pharmacology, University of Newcastle upon Tyne, UK.
Hum Toxicol. 1987 Nov;6(6):511-5. doi: 10.1177/096032718700600611.
The epidemiology of 737 consecutive self-poisoning admissions to Freeman Hospital, Newcastle upon Tyne, has been investigated with reference to age in young (less than 35), mid-aged (35-64) and elderly (greater than or equal to 65 year) patients. The most important differences were increased formal psychiatric illness in the elderly, demonstrated by increased likelihood of admission to psychiatric units; less likelihood of overdose with multiple agents in the elderly, and less use of alcohol. There were also differences in the types of drugs used. The youngest patients took more paracetamol and less psychoactive drugs and more of their drugs were prescribed for a relative than the other two groups. The elderly were much less likely to receive gastric lavage or emesis and more likely to receive supportive treatment only than younger patients. This difference may, in part, be explained by the more frequent occurrence of benzodiazepine poisoning in those over 65 years.
对纽卡斯尔市弗里曼医院连续收治的737例自我中毒患者进行了流行病学调查，调查对象分为年轻患者（小于35岁）、中年患者（35 - 64岁）和老年患者（大于或等于65岁）。最重要的差异包括：老年患者中正式的精神疾病增多，表现为入住精神科病房的可能性增加；老年患者服用多种药物过量的可能性较小，且饮酒较少。在用药类型上也存在差异。最年轻的患者服用对乙酰氨基酚较多，服用精神活性药物较少，且与其他两组相比，他们更多的药物是为亲属开具的。老年患者接受洗胃或催吐的可能性远低于年轻患者，而仅接受支持治疗的可能性更大。这种差异部分可能是由于65岁以上人群中苯二氮䓬类中毒更为常见。
