联合应用抗生素和光动力疗法治疗难治性海分枝杆菌感染：病例报告。
Combination treatment with antibiotics and photodynamic therapy in refractory mycobacterium marinum infection: A case report.
机构信息
Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jingshi Lu, Jinan, Shandong 27397, China.
Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jingshi Lu, Jinan, Shandong 27397, China.
出版信息
Photodiagnosis Photodyn Ther. 2023 Jun;42:103516. doi: 10.1016/j.pdpdt.2023.103516. Epub 2023 Mar 15.
Mycobacterium marinum can cause skin infection. Treatment of this infection often requires a chronic multidrug regimen. For refractory cases with progression, relapse, or slow recovery, long-term medication may cause problems such as ineffectiveness, poor patient compliance, and drug intolerance. We report a refractory case with a total treatment time of 2 years, successfully cured by the combination of antibiotics and photodynamic therapy. Our case shows that combination treatment with antibiotics and photodynamic therapy may be an effective approach for refractory Mycobacterium marinum infection.
海洋分枝杆菌可引起皮肤感染。这种感染的治疗通常需要长期的多药物方案。对于进展、复发或恢复缓慢的难治性病例，长期用药可能会导致无效、患者顺应性差和药物不耐受等问题。我们报告了一例难治性病例，总治疗时间为 2 年，通过抗生素和光动力疗法联合治疗成功治愈。我们的病例表明，抗生素和光动力疗法联合治疗可能是治疗难治性海洋分枝杆菌感染的有效方法。
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