School of Chemistry and Chemical Engineering, Huaiyin Normal University, Jiangsu Collaborative Innovation Center of Regional Modern Agriculture & Environmental Protection, No.111 West Changjiang Road, Huaian, 223300, Jiangsu Province, PR China; State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, Nanjing, 210009, PR China.
WA School of Mines: Minerals, Energy and Chemical Engineering (WASM-MECE), Curtin University, Perth, WA, 6102, Australia.
Anal Chim Acta. 2023 Apr 22;1251:341007. doi: 10.1016/j.aca.2023.341007. Epub 2023 Feb 25.
Non-enzymatic electrochemical sensors with significant advantages of high sensitivity, long-term stability, and excellent reproducibility, are one promising technology to solve many challenges, such as the detection of toxic substances and viruses. Among various materials, perovskite oxides have become a promising candidate for use in non-enzymatic electrochemical sensors because of their low cost, flexible structure, and high intrinsic catalytic activity. A comprehensive overview of the recent advances in perovskite oxides for non-enzymatic electrochemical sensors is provided, which includes the synthesis methods of nanostructured perovskites and the electrocatalytic mechanisms of perovskite catalysts. The better sensing performance of perovskite oxides is mainly due to the lattice O vacancies and superoxide oxygen ions (O/O), which are generated by the transfer of lattice oxygen to adsorbed -OH and have performed excellent properties suitable for electrooxidation of analytes. However, the limited electron transfer kinetics, stability, and selectivity of perovskite oxides alone make perovskite oxides far from ready for scientific development. Therefore, composites of perovskite oxides with other materials like graphitic carbon, metals, metal compounds, conducting organics, and biomolecules are summarized. Furthermore, a brief section describing the future challenges and the corresponding recommendation is presented in this review.
非酶电化学传感器具有灵敏度高、长期稳定性好、重现性优异等显著优势，是解决许多挑战的一种很有前途的技术，例如有毒物质和病毒的检测。在各种材料中，钙钛矿氧化物因其成本低、结构灵活和固有催化活性高而成为非酶电化学传感器的有前途的候选材料。本文全面概述了钙钛矿氧化物在非酶电化学传感器中的最新进展，包括纳米结构钙钛矿的合成方法和钙钛矿催化剂的电催化机制。钙钛矿氧化物具有更好的传感性能，主要是由于晶格 O 空位和超氧化物氧离子 (O/O) 的产生，晶格氧向吸附的 -OH 转移产生了这些空位和离子，从而表现出适合分析物电氧化的优异性能。然而，钙钛矿氧化物本身的电子转移动力学、稳定性和选择性有限，使得钙钛矿氧化物远未达到科学发展的水平。因此，本文总结了钙钛矿氧化物与其他材料（如石墨碳、金属、金属化合物、导电有机物和生物分子）的复合材料。此外，本文还在简短的总结部分描述了未来的挑战和相应的建议。
