Wang Yufeng, Yang Fangling, Liu Weilong, Fan Xiaofen, Lu Yong
Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
Front Surg. 2023 Feb 28;10:1134934. doi: 10.3389/fsurg.2023.1134934. eCollection 2023.
A palatal fistula following the closure of palatal clefts remains a difficult clinical complication. Surgical treatment of fistulas is often complicated, with high recurrence rates. We present our results of fistula closure augmented with GTR, a resorbable membrane designed to promote guided tissue regeneration.
We reviewed the records of 75 patients operated on between 2008 and 2022 for closure of the palatal fistula. The patients included 24 who underwent fistula closure augmented with GTR and 51 who underwent fistula closure with other techniques. We reviewed the age at surgery, sex, fistula location, and outcome. Operation success was defined as an asymptomatic patient with a healed fistula on clinical examination.
The overall fistula closure rate was 79.1% in the GTR group and 76.5% in the non-GTR group(= 0.79).
The success rate of fistula closure in the GTR group is comparable to that in the non-GTR group in this study. An additional advantage is that this procedure does not require harvesting any autologous tissue and reduces tissue damage in the long term.
腭裂修复术后的腭瘘仍然是一种棘手的临床并发症。瘘管的手术治疗往往很复杂，复发率很高。我们展示了使用GTR（一种旨在促进引导组织再生的可吸收膜）增强瘘管闭合的结果。
我们回顾了2008年至2022年间接受腭瘘闭合手术的75例患者的记录。患者包括24例接受GTR增强瘘管闭合的患者和51例接受其他技术瘘管闭合的患者。我们回顾了手术年龄、性别、瘘管位置和结果。手术成功定义为临床检查时无症状且瘘管愈合的患者。
GTR组的总体瘘管闭合率为79.1%，非GTR组为76.5%（=0.79）。
在本研究中，GTR组的瘘管闭合成功率与非GTR组相当。另一个优点是，该手术不需要采集任何自体组织，从长远来看减少了组织损伤。
