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直肠阴道瘘的手术修复:瘘管闭合的预测因素

Surgical repair of rectovaginal fistulas: predictors of fistula closure.

作者信息

Fu Jihong, Liang Zhonglin, Zhu Yilian, Cui Long, Chen Wei

机构信息

Department of Colorectal Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, China.

出版信息

Int Urogynecol J. 2019 Oct;30(10):1659-1665. doi: 10.1007/s00192-019-04082-w. Epub 2019 Aug 29.

Abstract

INTRODUCTION AND HYPOTHESIS

We report the clinical outcome of surgical repair for rectovaginal fistula (RVF) carried out by one operative team. We also investigate the predictive factors for fistula healing.

METHODS

A retrospective cohort of 63 patients underwent local surgical repair of RVF during January 2008 and December 2017 by one operative group. The clinical features of the patients were reviewed. The association between fistula closure and diverse clinical parameters, including operative method, fistula location, prior repair, and diverting stoma, was analyzed.

RESULTS

Sixty-three consecutive patients underwent 80 local surgical repairs by our surgical team. Forty-five patients eventually healed after an average of 1.22 procedures. The overall success rate per procedure was 71.2%, whereas the closure rate of the first operation was 55.5% (n = 35). The etiology of the fistula did not impact on the success rate of surgical repair. The history of prior repair predicted a lower success rate on both overall procedure (RR = 0.59, 95% CI 0.41-0.85, p = 0.008) and the first repair in our institution (RR = 0.50, 95% CI 0.31-0.80, p = 0.003). There was no difference in closure rate between the stoma group and the non-stoma group. Nevertheless, among the 15 patients who underwent more than one operation in our center, a diverting stoma seemed to be necessary (10 patients healed in the stoma group and none of the patients healed in the non-stoma group, p = 0.02).

CONCLUSIONS

History of prior surgical repair is a risk factor for failure. Diverting stoma did not increase the overall closure rate, but it seemed to be necessary for patients in whom the first operation failed.

摘要

引言与假设

我们报告了由一个手术团队进行的直肠阴道瘘(RVF)手术修复的临床结果。我们还研究了瘘管愈合的预测因素。

方法

回顾性队列研究63例患者,于2008年1月至2017年12月由一个手术组对其进行RVF局部手术修复。对患者的临床特征进行了回顾。分析了瘘管闭合与多种临床参数之间的关联,包括手术方法、瘘管位置、既往修复情况和转流造口。

结果

我们的手术团队对63例连续患者进行了80次局部手术修复。45例患者平均经过1.22次手术后最终愈合。每次手术的总体成功率为71.2%,而首次手术的闭合率为55.5%(n = 35)。瘘管的病因不影响手术修复的成功率。既往修复史预示着总体手术(RR = 0.59,95%CI 0.41 - 0.85,p = 0.008)以及在我们机构进行的首次修复(RR = 0.50,95%CI 0.31 - 0.80,p = 0.003)的成功率较低。造口组和非造口组的闭合率没有差异。然而,在我们中心接受不止一次手术的15例患者中,似乎需要进行转流造口(造口组10例患者愈合,非造口组无患者愈合,p = 0.02)。

结论

既往手术修复史是失败的危险因素。转流造口并未提高总体闭合率,但对于首次手术失败的患者似乎是必要的。

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