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用于治疗儿科患者非囊状动脉瘤的管道栓塞装置。

Pipeline embolization devices for the treatment of nonsaccular aneurysms in pediatric patients.

作者信息

Han Jintao, Liang Fei, Zhang Yuxiang, Zhang Yupeng, Liang Shikai, Zhu Haoyu, Chang Yuzhou, Ma Chao, Liu Lian, Jia Zichang, Jiang Chuhan

机构信息

Department of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing, China.

Department of Neurosurgery, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

出版信息

Front Neurol. 2023 Feb 28;14:1115618. doi: 10.3389/fneur.2023.1115618. eCollection 2023.

Abstract

OBJECTIVE

Pediatric nonsaccular aneurysms are rare but challenging lesions; pipeline embolization devices (PEDs) are their potential treatment option. In this study, we aimed to evaluate the safety and efficacy of PEDs for treatment of these aneurysms.

METHODS

We retrospectively selected pediatric patients with nonsaccular aneurysms treated using PEDs between June 2015 and July 2021 from our prospectively maintained database. For each patient, demographics, aneurysm characteristics, procedure details, and clinical and angiographic follow-up data were collected and summarized.

RESULTS

This study included 16 pediatric patients with 16 nonsaccular aneurysms treated with PEDs. A median clinical follow-up time of 1,376 days was achieved in 93.75% of the patients. The complication rate of the included patients was 25%, with two patients developing mass effect, one patient undergoing major ischemic stroke, and one patient experiencing stent foreshortening after the procedure. The complete occlusion rate of aneurysms without any neurologic sequelae was 93.33%, with a median angiographic follow-up period of 246 days. The mortality rate was 6.25%.

CONCLUSIONS

The use of PEDs to treat pediatric nonsaccular aneurysms is feasible, with a high rate of complete occlusion of the aneurysm and favorable follow-up outcomes.

摘要

目的

小儿非囊状动脉瘤罕见但具有挑战性;血流导向装置(PEDs)是其潜在的治疗选择。在本研究中,我们旨在评估PEDs治疗这些动脉瘤的安全性和有效性。

方法

我们从前瞻性维护的数据库中回顾性选择了2015年6月至2021年7月间使用PEDs治疗的小儿非囊状动脉瘤患者。收集并总结了每位患者的人口统计学资料、动脉瘤特征、手术细节以及临床和血管造影随访数据。

结果

本研究纳入了16例接受PEDs治疗的小儿非囊状动脉瘤患者。93.75%的患者临床随访时间中位数为1376天。纳入患者的并发症发生率为25%,2例出现占位效应,1例发生严重缺血性卒中,1例术后出现支架缩短。无任何神经后遗症的动脉瘤完全闭塞率为93.33%,血管造影随访期中位数为246天。死亡率为6.25%。

结论

使用PEDs治疗小儿非囊状动脉瘤是可行的,动脉瘤完全闭塞率高,随访结果良好。

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