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评估影响小儿心脏手术后快速通道或早期拔管的因素。

Assessment of the factors that affect fast-track or early extubation following pediatric cardiac surgery.

作者信息

Özalp Şerife, Dilek Özcanoğlu Hatice, Öztürk Erkut, Sağlam Selin, Kahraman İncila Ali, Tan Zümrüt Berra, Yıldız Okan, Özcan Funda Gümüş, Hatemi Ali Can

机构信息

Department of Anaesthesiology and Reanimation, Health Sciences University, Başakşehir Cam and Sakura Hospital, Istanbul, Türkiye.

Department of Pediatric Cardiology, Health Sciences University, Başakşehir Cam and Sakura Hospital, Istanbul, Türkiye.

出版信息

Turk Gogus Kalp Damar Cerrahisi Derg. 2023 Jan 30;31(1):1-7. doi: 10.5606/tgkdc.dergisi.2023.23206. eCollection 2023 Jan.

Abstract

BACKGROUND

This study aims to evaluate the early extubation rate and the factors affecting early extubation in pediatric patients undergoing cardiac surgery.

METHODS

Between August 1st, 2020 and December 1st, 2021, a total of 528 pediatric patients (264 males, 264 females; median age: 4 months; range, 2 days to 24 months) who were followed in the pediatric cardiac intensive care unit after congenital heart surgery were retrospectively analyzed. Demographic and clinical characteristics of the patients including operation and intensive care data were obtained from the medical records. Patients included in the study were categorized into three groups as the group of patients who were extubated in the operating room (fast-track extubation), the group of patients who were extubated in the first 6 h of the operation (early extubation), the group of patients who were extubated after the postoperative 6 h or the group of patients who were not extubated or died (delayed extubation).

RESULTS

Sixty-eight (12.9%) cases had fast-tract extubation, 124 (23.6%) cases had early extubation, and 335 (63.6%) cases had delayed extubation. The median age of the patients in the delayed extubation group was three months, which was significantly lower than those of the other groups (p<0.05). Reintubation rates were 1.5% in the fast-tract extubation group, 2.5% in early extubation group, and 9% in delayed extubation group (p<0.05). The median intensive care unit stay was 3, 5, and 10 days, respectively (p<0.05). Length of hospitalization was significantly higher in the delayed extubation group compared to the other groups (p<0.05). Neonatal age group, Risk Adjustment for Congenital Heart Surgery 1 score >4, Society of Thoracic Surgeons- European Association for Cardio-Thoracic Surgery mortality category >3, cardiopulmonary bypass time >100/min, vasoactive inotrope score >8, acute kidney injury >2, and low weight were found to be independent risk factors for delayed extubation.

CONCLUSION

Fast-track and early extubation can be successfully applied with low reintubation rates in selected cases with congenital heart surgery. Age, body weight, presence of genetic syndrome, operational risk category, and procedure time may affect the extubation time.

摘要

背景

本研究旨在评估接受心脏手术的儿科患者的早期拔管率及影响早期拔管的因素。

方法

回顾性分析2020年8月1日至2021年12月1日期间,在小儿心脏重症监护病房接受先天性心脏病手术后随访的528例儿科患者(男264例,女264例;中位年龄:4个月;范围:2天至24个月)。从病历中获取患者的人口统计学和临床特征,包括手术及重症监护数据。纳入研究的患者分为三组:在手术室拔管的患者组(快速拔管)、手术开始后6小时内拔管的患者组(早期拔管)、术后6小时后拔管的患者组或未拔管或死亡的患者组(延迟拔管)。

结果

68例(12.9%)患者快速拔管,124例(23.6%)患者早期拔管,335例(63.6%)患者延迟拔管。延迟拔管组患者的中位年龄为3个月,显著低于其他组(p<0.05)。快速拔管组的再插管率为1.5%,早期拔管组为2.5%,延迟拔管组为9%(p<0.05)。重症监护病房的中位住院时间分别为3天、5天和10天(p<0.05)。延迟拔管组的住院时间显著高于其他组(p<0.05)。发现新生儿年龄组、先天性心脏病手术风险调整1评分>4、胸外科医师协会-欧洲心胸外科协会死亡率类别>3、体外循环时间>100分钟、血管活性药物评分>8、急性肾损伤>2和低体重是延迟拔管的独立危险因素。

结论

在先天性心脏病手术的特定病例中,快速拔管和早期拔管可成功应用,且再插管率较低。年龄、体重、遗传综合征的存在、手术风险类别和手术时间可能影响拔管时间。

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