Wu Keye, Chen Fang, Wang Yuanxiang, Ti Yunxing, Liu Huaipu, Wang Pengcheng, Ding Yiqun
Department of Cardiac Surgery, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
Department of Anesthesiology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
Heart Lung Circ. 2020 Sep;29(9):e238-e244. doi: 10.1016/j.hlc.2020.01.004. Epub 2020 Feb 7.
Early extubation has become widely adopted in cardiac surgery practices. This study aimed to present experience of early extubation after congenital heart surgery and to explore the factors that affect successful immediate postoperative extubation and early extubation.
A retrospective analysis was performed of all patients who underwent congenital heart surgery with cardiopulmonary bypass (CPB) at Shenzhen Children's Hospital between 01 May 2015 and 30 September 2019. The demographic and cardiac surgery information were derived from the medical records. Multivariable logistic regression models were used to explore the influence factors for successful immediate postoperative extubation and early extubation.
This study consisted of 2,060 patients, 65.0% of whom were extubated in the operating room and 16.1% of whom were extubated early (within 6 hours) in the Intensive Care Unit. The overall rates of reintubation and nasal continuous positive airway pressure were 2.0% and 6.4%, respectively. Preoperative weight (OR, 1.24; 95% CI, 1.20-1.29), preoperative pneumonia (OR, 0.60; 95% CI, 0.44-0.80), CPB type (OR, 1.23; 95% CI, 1.06-1.43), CPB time (OR, 0.98; 95% CI, 0.98-0.99), deep hypothermic circulatory arrest (OR, 0.42; 95% CI, 0.25-0.70), and Society of Thoracic Surgeons-European Association for Cardiothoracic Surgery Congenital Heart Surgery (STAT) categories (OR, 0.54; 95% CI, 0.45-0.65) were included in the immediate postoperative extubation model. In addition to the above six variables, ultrafiltration (OR, 0.63; 95% CI, 0.44-0.89) was also included in the early extubation model. Similar results were found in the immediate postoperative extubation model for non-newborns. The influencing factors for early extubation in the non-newborn population included preoperative weight, preoperative pneumonia, ultrafiltration, CPB time, and STAT categories.
Early extubation for children with congenital heart surgery was successful in this hospital. Patients with early extubation had a lower reintubation rate and nasal continuous positive airway pressure rate, and a shorter length of stay in the ICU and hospital. Early extubation was influenced by age, weight at surgery, preoperative pneumonia, CPB type, CPB time, deep hypothermic circulatory arrest, ultrafiltration, and STAT categories.
早期拔管已在心脏外科手术中广泛应用。本研究旨在介绍先天性心脏病手术后早期拔管的经验,并探讨影响术后即刻成功拔管和早期拔管的因素。
对2015年5月1日至2019年9月30日在深圳儿童医院接受体外循环(CPB)先天性心脏病手术的所有患者进行回顾性分析。人口统计学和心脏手术信息来自病历。采用多变量逻辑回归模型探讨术后即刻成功拔管和早期拔管的影响因素。
本研究共纳入2060例患者,其中65.0%在手术室拔管,16.1%在重症监护病房(ICU)早期(6小时内)拔管。再次插管和经鼻持续气道正压通气的总体发生率分别为2.0%和6.4%。术后即刻拔管模型纳入了术前体重(OR,1.24;95%CI,1.20 - 1.29)、术前肺炎(OR,0.60;95%CI,0.44 - 0.80)、CPB类型(OR,1.23;95%CI,1.06 - 1.43)、CPB时间(OR,0.98;95%CI,0.98 - 0.99)、深度低温循环停搏(OR,0.42;95%CI,0.25 - 0.70)以及胸外科医师协会 - 欧洲心胸外科学会先天性心脏病手术(STAT)分类(OR,0.54;95%CI,0.45 - 0.65)。除上述六个变量外,早期拔管模型还纳入了超滤(OR,0.63;95%CI,0.44 - 0.89)。在非新生儿的术后即刻拔管模型中也发现了类似结果。非新生儿人群早期拔管的影响因素包括术前体重、术前肺炎、超滤、CPB时间和STAT分类。
本院先天性心脏病手术患儿早期拔管取得成功。早期拔管患者的再次插管率和经鼻持续气道正压通气率较低,在ICU和医院的住院时间较短。早期拔管受年龄、手术时体重、术前肺炎、CPB类型、CPB时间、深度低温循环停搏、超滤和STAT分类的影响。