Puget Sound Health Care System, Seattle, WA.
MultiCare Auburn Medical Center, Auburn, WA.
Wounds. 2023 Mar;35(3):E98-E101. doi: 10.25270/wnds/22045.
Mucormycosis is a rare but serious angioinvasive fungal infection that can affect the cutaneous system. Primary cutaneous mucormycosis is caused by direct inoculation and is most prevalent in immunocompromised hosts, particularly those with diabetes. A high index of suspicion is necessary for this condition in patients with rapid and deep extension of necrosis despite aggressive surgical intervention. Deep tissue specimens should be sent for fungal culture and histologic analysis for confirmation of the diagnosis. Early and aggressive debridement to prevent spread to deeper tissues and organs, concurrent antifungal therapy, and medical management of comorbidities are paramount to the treatment of primary cutaneous mucormycosis.
This case report highlights the presentation and recommended treatment of primary cutaneous mucormycosis in 1 patient for reduced morbidity and mortality associated with this type of infection.
毛霉病是一种罕见但严重的血管侵袭性真菌感染,可影响皮肤系统。原发性皮肤毛霉病由直接接种引起,在免疫功能低下的宿主中更为常见,特别是那些患有糖尿病的患者。对于此类疾病,在积极的手术干预下,患者的坏死仍迅速且深度扩展,应高度怀疑。为了确诊,应将深部组织标本送去进行真菌培养和组织学分析。早期且积极地清创以防止感染扩散到更深的组织和器官,同时进行抗真菌治疗,并对合并症进行医学管理,这些对于治疗原发性皮肤毛霉病至关重要。
本病例报告重点介绍了 1 例原发性皮肤毛霉病的表现和推荐治疗方法,以降低与这种类型的感染相关的发病率和死亡率。