Department of Internal Medicine, Division of Cancer Prevention and Control, The Ohio State University, Columbus, Ohio, United States of America.
Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, Ohio, United States of America.
PLoS One. 2023 Mar 16;18(3):e0282719. doi: 10.1371/journal.pone.0282719. eCollection 2023.
Weight loss through lifestyle modification can produce health benefits and may reduce cancer risk. The goal of this study was to examine the feasibility of and adherence to a 15-week telephone-based weight loss intervention in rural Ohio, an area with high rates of obesity.
This pilot 2-arm randomized controlled study was designed for rural Ohio residents who were overweight or obese. Eligible participants were 2:1 randomly assigned to either a 15-week weight loss intervention group or active control group. The weight loss intervention group received weekly telephone sessions to improve healthy diet and increase physical activity. The active control group received education brochures with information on physical activity and dietary guidelines. Feasibility was defined as at least 80% of participants completing the follow-up surveys, and acceptable adherence was defined as the percentage of participants in the weight loss group who attend ≥75% of weekly telephone sessions.
A total of 423 individuals entered the online screening survey, 215 (50.8%) completed the survey, and 98 (45.6%) of those were eligible. Forty eligible individuals were enrolled and randomly assigned to the weight loss group (n = 27) or active control group (n = 13). The average age of the weight loss group was 49 (SD = 10) years, and 89% were female. The average age of the active control group was 51 (SD = 9) years, and 92% were female. Feasibility was demonstrated: 90% of participants completed the online follow-up surveys at 15-weeks. Among participants in the weight loss group, 22 out of 27 (81.5%) completed the 15-week intervention, the average number of sessions attended was 9.7 (64.9%). Adherence to the intervention was rated as acceptable among almost half of the group (48.1%).
Feasibility of a 15-week telephone-based weight loss study among rural residents with overweight/obesity were determined. A future study will test this intervention for weight loss efficacy.
通过生活方式改变来减肥可以带来健康益处，并可能降低癌症风险。本研究的目的是检验在俄亥俄州农村地区进行为期 15 周的电话式减肥干预的可行性和依从性，该地区肥胖率很高。
这是一项 2 臂随机对照的试点研究，对象为超重或肥胖的俄亥俄州农村居民。符合条件的参与者以 2:1 的比例随机分配到为期 15 周的减肥干预组或活动对照组。减肥干预组每周接受电话访谈以改善健康饮食和增加身体活动。活动对照组收到有关身体活动和饮食指南的教育手册。可行性定义为至少 80%的参与者完成随访调查，可接受的依从性定义为减肥组中参加每周电话访谈≥75%的参与者的百分比。
共有 423 人参加了在线筛查调查，215 人（50.8%）完成了调查，其中 98 人（45.6%）符合条件。40 名符合条件的参与者被纳入并随机分配到减肥组（n = 27）或活动对照组（n = 13）。减肥组的平均年龄为 49 岁（SD = 10），89%为女性。活动对照组的平均年龄为 51 岁（SD = 9），92%为女性。可行性得到了证明：90%的参与者在 15 周时完成了在线随访调查。在减肥组中，27 名参与者中有 22 名（81.5%）完成了 15 周的干预，参加的访谈平均次数为 9.7 次（64.9%）。该干预措施的依从性在近一半的参与者中被评为可接受（48.1%）。
确定了在超重/肥胖的农村居民中进行为期 15 周的电话式减肥研究的可行性。未来的研究将测试该干预措施对减肥效果的影响。
