Internal Medicine Resident, Department of Cardiology, The First Affiliated Hospital of Yangtze University, Jingzhou, China.
Department of Cardiology, The First Affiliated Hospital of Yangtze University, Jingzhou, China.
Medicine (Baltimore). 2023 Mar 17;102(11):e33298. doi: 10.1097/MD.0000000000033298.
To analyze existing literature and understand how to balance the minimization of bleeding risk and ensuring adequate anticoagulation during coronary intervention treatment and long-term postoperative anticoagulation in hemophilia patients during the perioperative period, in order to provide guidance for healthcare professionals in developing effective treatment plans. This narrative review will analyze existing studies, case reports, and clinical guidelines to determine the most effective strategies for managing acute coronary syndrome in hemophilia patients. When evaluating the literature, factors such as patient age, medical history, and severity of the condition will be considered. The current management guidelines for acute coronary syndrome in hemophilia patients are not based on systematic evaluation and mainly rely on expert opinions. This article provides a comprehensive analysis of existing literature and recommends coagulation factor replacement therapy before anticoagulation and intervention treatment, as well as personalized anticoagulation treatment during the postoperative period for better management of hemophilia patients with acute coronary syndrome. These recommendations can help healthcare professionals develop more effective treatment plans for hemophilia patients.
为了分析现有的文献，并了解如何在围手术期平衡血友病患者的出血风险最小化和确保充分抗凝，以提供指导医疗保健专业人员制定有效的治疗计划。本叙述性综述将分析现有的研究、病例报告和临床指南，以确定管理血友病患者急性冠状动脉综合征的最有效策略。在评估文献时，将考虑患者年龄、病史和病情严重程度等因素。目前血友病患者急性冠状动脉综合征的管理指南不是基于系统评价，主要依赖于专家意见。本文对现有文献进行了全面分析，并建议在抗凝和介入治疗前进行凝血因子替代治疗，以及在术后个体化抗凝治疗，以更好地管理急性冠状动脉综合征的血友病患者。这些建议可以帮助医疗保健专业人员为血友病患者制定更有效的治疗计划。
