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COVID-19:建立、实施和评估安全策略,描述性干预研究。

COVID-19: Establishing, implementing and assessment safety strategy, descriptive interventional study.

机构信息

Medical Laboratory Technology Department, Faculty of Applied Medical Science, University of Tabuk, Tabuk, Saudi Arabia.

Department of Microbiology and Immunology, Faculty of Medical Laboratory Science, Alzaiem Alazhari University, Khartoum, Sudan.

出版信息

PLoS One. 2023 Mar 17;18(3):e0283197. doi: 10.1371/journal.pone.0283197. eCollection 2023.

Abstract

The increase in severe acute respiratory syndrome SARS-CoV-2 has invariably affected medical professionals in their training, academic and professional development. The present study was an interventional descriptive study aimed at reducing the risk of exposure to COVID-19 and enabling physical attendance to the practical session for applied medical students by establishing and implementing a safety strategy. The adopted safety strategy has eight conditions and 50 requirements. Compliance with the safety strategy along with the serological diagnosis of COVID-19 was used as a key performance indicator for assessing the efficiency of the safety strategy. A total of 197 students were enrolled at the beginning of the study. The overall results showed that 78.1% of the respondents strictly followed the protocol, 14.5% of the individuals partially responded to the protocol and 7.4% of the individuals did not respond to the protocol. Twenty-two (12.6%) out of the 175 participants who completed the study had positive COVID-19 during the study period, whereas the remaining 153 participants (87.4%) appeared to be healthy. The serological results showed that 68 (38.9%) and 66 (37.7%) individuals of the study population had positive IgM+IgA and IgG of COVID-19, respectively; the majority of the participants who developed antibodies did not show symptoms and appeared to be healthy during the study. The physical distancing condition was the only condition that displayed a significant relationship with seropositive IgM+IgA. The compiling of standardized protocols along with serological diagnoses can be an effective tool in measuring the effectiveness of safety protocol and reducing the risk of exposure to COVID-19.

摘要

严重急性呼吸系统综合征(SARS-CoV-2)的病例不断增加,这对医疗专业人员的培训、学术和专业发展产生了重大影响。本研究是一项干预性描述性研究,旨在通过建立和实施安全策略,降低接触 COVID-19 的风险,并使应用医学专业学生能够实际参加实践课程。所采用的安全策略有八项条件和五十项要求。遵守安全策略以及 COVID-19 的血清学诊断,被用作评估安全策略效率的关键绩效指标。在研究开始时,共有 197 名学生入组。总体结果表明,78.1%的受访者严格遵守了方案,14.5%的人部分响应了方案,7.4%的人没有响应方案。在完成研究的 175 名参与者中,有 22 人(12.6%)在研究期间 COVID-19 检测呈阳性,而其余 153 人(87.4%)似乎健康。血清学结果表明,研究人群中有 68 人(38.9%)和 66 人(37.7%)的 COVID-19 血清 IgM+IgA 和 IgG 呈阳性;大多数产生抗体的参与者没有出现症状,在研究期间表现健康。保持身体距离是唯一与血清阳性 IgM+IgA 呈显著相关的条件。标准化方案的编制以及血清学诊断可以是衡量安全方案有效性和降低 COVID-19 暴露风险的有效工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc26/10022754/fba75e23dac3/pone.0283197.g001.jpg

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