Wu Yuzheng, Xiao Dezhi, Liu Pei, Liao Qing, Ruan Qingdong, Huang Chao, Liu Liangliang, Li Dan, Zhang Xiaolin, Li Wei, Tang Kaiwei, Wu Zhengwei, Wang Guomin, Wang Huaiyu, Chu Paul K
Department of Physics, Department of Materials Science and Engineering and Department of Biomedical Engineering, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China.
Center for Human Tissues and Organs Degeneration, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Research (Wash D C). 2023;6:0074. doi: 10.34133/research.0074. Epub 2023 Mar 10.
The power generated by flexible wearable devices (FWDs) is normally insufficient to eradicate bacteria, and many conventional antibacterial strategies are also not suitable for flexible and wearable applications because of the strict mechanical and electrical requirements. Here, polypyrrole (PPy), a conductive polymer with a high mass density, is used to form a nanostructured surface on FWDs for antibacterial purposes. The conductive films with PPy nanorods (PNRs) are found to sterilize 98.2 ± 1.6% of and 99.6 ± 0.2% of upon mild electrification (1 V). Bacteria killing stems from membrane stress produced by the PNRs and membrane depolarization caused by electrical neutralization. Additionally, the PNR films exhibit excellent biosafety and electrical stability. The results represent pioneering work in fabricating antibacterial components for FWDs by comprehensively taking into consideration the required conductivity, mechanical properties, and biosafety.
柔性可穿戴设备（FWDs）产生的电力通常不足以根除细菌，而且由于严格的机械和电气要求，许多传统的抗菌策略也不适用于柔性和可穿戴应用。在此，聚吡咯（PPy）是一种具有高质量密度的导电聚合物，被用于在FWDs上形成纳米结构表面以实现抗菌目的。发现带有聚吡咯纳米棒（PNRs）的导电膜在轻度通电（1V）时能杀灭98.2±1.6%的[具体细菌1]和99.6±0.2%的[具体细菌2]。细菌杀灭源于PNRs产生的膜应力和电中和引起的膜去极化。此外，PNR膜表现出优异的生物安全性和电稳定性。这些结果代表了在通过综合考虑所需的导电性、机械性能和生物安全性来制造FWDs抗菌组件方面的开创性工作。
