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Universal Germline and Tumor Genomic Testing Needed to Win the War Against Cancer: .

作者信息

Subbiah Vivek, Kurzrock Razelle

机构信息

Department of Investigational Cancer Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.

Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX.

出版信息

J Clin Oncol. 2023 Jun 10;41(17):3100-3103. doi: 10.1200/JCO.22.02833. Epub 2023 Mar 17.

DOI:10.1200/JCO.22.02833
PMID:36930859
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10256401/
Abstract
摘要

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Characterization of Oncology Clinical Trials Using Germline Genetic Data.基于胚系遗传数据的肿瘤临床试验特征分析。
JAMA Netw Open. 2022 Nov 1;5(11):e2242370. doi: 10.1001/jamanetworkopen.2022.42370.
3
Accelerated approvals hit the target in precision oncology.加速批准在精准肿瘤学领域命中目标。
Nat Med. 2022 Oct;28(10):1976-1979. doi: 10.1038/s41591-022-01984-z.
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Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors.基于祖源的肿瘤突变负荷重新校准与免疫检查点抑制剂反应的不同临床结局。
Cancer Cell. 2022 Oct 10;40(10):1161-1172.e5. doi: 10.1016/j.ccell.2022.08.022. Epub 2022 Sep 29.
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Clinical Utility of Universal Germline Genetic Testing for Patients With Breast Cancer.乳腺癌患者进行通用种系基因检测的临床实用性。
JAMA Netw Open. 2022 Sep 1;5(9):e2232787. doi: 10.1001/jamanetworkopen.2022.32787.
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