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混合气变化过程中恒压下高压神经综合征的发生情况。

Occurrence of high-pressure nervous syndrome at constant pressure during change of mixture.

作者信息

Rostain J C, Gardette-Chauffour M C, Naquet R

机构信息

Centre National de la Recherche Scientifique, Faculté de Médecine Nord, Marseille, France.

出版信息

J Appl Physiol (1985). 1987 Nov;63(5):1919-25. doi: 10.1152/jappl.1987.63.5.1919.

DOI:10.1152/jappl.1987.63.5.1919
PMID:3693227
Abstract

Three professional divers have performed a dive to 450 msw. From 200 msw and during the first 64 h on the bottom, they breathed a H2-He-O2 mixture with 54-56% H2. At this time a switch was performed to a mixture with 30% H2, and 8 h later a second switch was performed to 0% H2. In the H2-He-O2 mixture the clinical symptoms of high-pressure nervous syndrome (HPNS) were not present and the electroencephalogram changes were slight. The switch of the mixture induced an isobaric HPNS of high intensity. Twenty-four hours later the HPNS decreased, but the clinical symptoms persisted throughout the stay in the He-O2 mixture. The appearance of isobaric HPNS during the switch might be due to the disappearance of the narcotic substance which suppressed or masked the clinical symptoms; it might also be due to the sudden increase in the partial pressure of He, which was equivalent to a fast compression.

摘要

三名职业潜水员潜入了450米海水深度。从200米海水深度开始以及在海底的最初64小时内,他们呼吸的是含54 - 56%氢气的氢气 - 氦气 - 氧气混合气。此时,更换为含30%氢气的混合气,8小时后再次更换为含0%氢气的混合气。在氢气 - 氦气 - 氧气混合气中,高压神经综合征(HPNS)的临床症状未出现,脑电图变化轻微。混合气的更换引发了高强度的等压HPNS。24小时后,HPNS有所减轻,但在整个停留于氦气 - 氧气混合气期间临床症状持续存在。更换过程中等压HPNS的出现可能是由于抑制或掩盖临床症状的麻醉物质消失;也可能是由于氦气分压突然升高,这相当于快速加压。

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