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2000 年至 2019 年美国全国孕产妇死亡率趋势中的种族差异:基于 8000 万活产人口的研究。

Racial disparities in national maternal mortality trends in the United States from 2000 to 2019: a population-based study on 80 million live births.

机构信息

Division of Experimental Medicine, McGill University, Montreal, QC, Canada.

Center for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, Montreal, QC, Canada.

出版信息

Arch Gynecol Obstet. 2024 Apr;309(4):1315-1322. doi: 10.1007/s00404-023-06999-6. Epub 2023 Mar 18.

Abstract

PURPOSE

In the United States (US), deaths during pregnancy and childbirth have increased over the past 2 decades compared to other high-income countries, and there have been reports that racial disparities in maternal mortality have widened. The study objective was to examine recent trends in maternal mortality in the US by race.

METHODS

Our population-based cross-sectional study used data from the Centers for Disease Control and Prevention's 2000-2019 "Birth Data" and "Mortality Multiple Cause" data files from the US to calculate maternal mortality during pregnancy, childbirth, and puerperium across race. Logistic regression models estimated the effects of race on the risk of maternal mortality and examined temporal changes in risk across race.

RESULTS

A total of 21,241 women died during pregnancy and childbirth, with 65.5% caused by obstetrical complications and 34.5% by non-obstetrical causes. Black women, compared with White women, had greater risk of maternal mortality (OR 2.13, 95% CI 2.06-2.20), as did American Indian women (2.02, 1.83-2.24). Overall maternal mortality risk increased during the 20-year study period, with an annual increase of 2.4 and 4.7/100,000 among Black and American Indian women, respectively.

CONCLUSIONS

Between 2000 and 2019, maternal mortality in the US increased, overall and especially in American Indian and Black women. Targeted public health interventions to improve maternal health outcomes should become a priority.

摘要

目的

在美国,与其他高收入国家相比,过去 20 年来妊娠和分娩期间的死亡人数有所增加,并且有报告称,孕产妇死亡率的种族差异有所扩大。本研究旨在通过种族来检验美国最近孕产妇死亡率的趋势。

方法

本基于人群的横断面研究使用了美国疾病控制与预防中心 2000-2019 年“生育数据”和“死亡多因”数据文件中的数据,按种族计算妊娠、分娩和产褥期的孕产妇死亡率。逻辑回归模型估计了种族对孕产妇死亡率风险的影响,并检查了种族之间风险的时间变化。

结果

共有 21241 名妇女在妊娠和分娩期间死亡,其中 65.5%由产科并发症引起,34.5%由非产科原因引起。与白人妇女相比,黑人妇女的孕产妇死亡率风险更高(OR 2.13,95%CI 2.06-2.20),美国印第安妇女的风险也更高(2.02,1.83-2.24)。在 20 年的研究期间,整体孕产妇死亡率风险增加,黑人妇女和美国印第安妇女的年增长率分别为 2.4 和 4.7/100000。

结论

2000 年至 2019 年间,美国的孕产妇死亡率总体上有所上升,尤其是在黑人妇女和美国印第安妇女中上升更为明显。有针对性的公共卫生干预措施应成为改善孕产妇健康结局的优先事项。

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