Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), China Pharmaceutical University, Nanjing 210009, PR China; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, PR China.
Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), China Pharmaceutical University, Nanjing 210009, PR China; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, PR China.
Food Chem. 2023 Aug 15;417:135920. doi: 10.1016/j.foodchem.2023.135920. Epub 2023 Mar 8.
Highly photoluminescent N-doped carbon quantum dots (N-CDs) which the quantum yield reached 63% were prepared through hydrothermal treatment. The obtained N-CDs displayed a uniform distribution of particle size, superior stability in high-salt conditions, and excellent sensitivity. A green fluorescence probe based on N-CDs was constructed for ultrasensitive determination of myricetin in vine tea on account of the static quenching. The N-CDs presented excellent linear fluorescence response in the concentration range of 0.2-40 μM and 56-112 μM and with a low detection limit of 56 nM. Additionally, the practicability of the probe was verified in spiked vine tea sample, and the satisfactory recoveries of myricetin varied from 98.8% to 101.2%, with relative standard deviations in the range of 1.52%-3.48%. It is the first time to employ N-CDs without any material modification as a fluorescence sensor to detect myricetin, which is a promising approach to expand the path for myricetin screening.
通过水热法制备了具有高达 63%量子产率的高发光 N 掺杂碳量子点（N-CDs）。所得到的 N-CDs 表现出粒径分布均匀、在高盐条件下稳定性好、灵敏度高的特点。基于 N-CDs 构建了一种绿色荧光探针，用于超灵敏测定藤茶中的杨梅素，这是由于静态猝灭。N-CDs 在 0.2-40 μM 和 56-112 μM 的浓度范围内表现出优异的线性荧光响应，检测限低至 56 nM。此外，该探针在加标藤茶样品中的实用性得到了验证，杨梅素的回收率在 98.8%至 101.2%之间，相对标准偏差在 1.52%-3.48%范围内。这是首次将未经任何材料修饰的 N-CDs 用作荧光传感器来检测杨梅素，这为杨梅素的筛选开辟了一条有前景的途径。
