薄膜切口滤波器作为生物图像处理的平台。

Thin film notch filters as platforms for biological image processing.

机构信息

ARC Centre of Excellence for Transformative Meta-Optical Systems, School of Physics, The University of Melbourne, Melbourne, VIC, 3010, Australia.

ARC Centre of Excellence for Transformative Meta-Optical Systems, Department of Electrical and Electronic Engineering, The University of Melbourne, Melbourne, VIC, 3010, Australia.

出版信息

Sci Rep. 2023 Mar 18;13(1):4494. doi: 10.1038/s41598-023-31528-5.

DOI:10.1038/s41598-023-31528-5

PMID:36934126

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10024701/

Abstract

Many image processing operations involve the modification of the spatial frequency content of images. Here we demonstrate object-plane spatial frequency filtering utilizing the angular sensitivity of a commercial spectral bandstop filter. This approach to all-optical image processing is shown to generate real-time pseudo-3D images of transparent biological and other samples, such as human cervical cancer cells. This work demonstrates the potential of non-local, non-interferometric approaches to image processing for uses in label-free biological cell imaging and dynamical monitoring.

摘要

许多图像处理操作都涉及到图像空间频率内容的修改。在这里，我们展示了利用商业带阻滤波器的角度灵敏度进行物面空间频率滤波。这种全光学图像处理方法被用于实时生成透明生物和其他样品的伪 3D 图像，例如人宫颈癌细胞。这项工作证明了非局部、非干涉图像处理方法在无标记生物细胞成像和动态监测中的应用潜力。