Remedee Labs, 99 chemin de l'étoile, 38330 Montbonnot St Martin, France; Univ. Grenoble Alpes, CNRS, UMR 5525, VetAgro Sup, Grenoble INP, TIMC, MESP, 38000 Grenoble, France.
AGIR à dom, 36 chemin du Vieux Chêne, 38240 Meylan, France.
Diabetes Res Clin Pract. 2023 May;199:110630. doi: 10.1016/j.diabres.2023.110630. Epub 2023 Mar 18.
The aim of this study was to determine the prevalence of likely eating disorders and insulin misuse in a prospective cohort of adults with type 1 diabetes mellitus (T1DM) treated with insulin pump therapy.
This prospective study was held at the participants' home. The participants completed the SCOFF questionnaire as well as a question related to insulin misuse. Information about lifestyle, medical history, insulin pump and Continuous Glucose Monitoring (CGM) data were collected.
The analysis covered 198 participants with a median age of 51 [95% CI 38; 62] years. The prevalence of likely eating disorders was 21.7% (95% CI 16.3; 28.2) in the study population and 20.6% (95% CI 14.3; 28.6) and 24.2% (95% CI 14.6; 37.0) in males and females respectively. The prevalence of insulin misuse was 39.0% (95% CI 30.8; 47.7). There was no significant difference in prevalence between males and females for likely eating disorders and insulin misuse. The analysis of CGM data revealed no factors related to glycaemic control associated with likely eating disorders.
The results of this study indicate that the prevalence of likely eating disorders is high even in a middle-aged population with a T1DM and satisfactory glucose control.
本研究旨在确定接受胰岛素泵治疗的 1 型糖尿病(T1DM)成人前瞻性队列中可能的饮食失调和胰岛素滥用的流行率。
这项前瞻性研究在参与者的家中进行。参与者完成了 SCOFF 问卷以及与胰岛素滥用相关的问题。收集了有关生活方式、病史、胰岛素泵和连续血糖监测(CGM)数据的信息。
分析涵盖了 198 名中位年龄为 51 岁[95%可信区间 38;62]的参与者。研究人群中可能的饮食失调患病率为 21.7%(95%可信区间 16.3;28.2),男性和女性分别为 20.6%(95%可信区间 14.3;28.6)和 24.2%(95%可信区间 14.6;37.0)。胰岛素滥用的患病率为 39.0%(95%可信区间 30.8;47.7)。男性和女性之间在可能的饮食失调和胰岛素滥用的患病率方面没有显著差异。CGM 数据的分析没有发现与血糖控制相关的可能饮食失调的相关因素。
本研究结果表明,即使在 T1DM 且血糖控制满意的中年人群中,可能的饮食失调患病率也很高。