Department of Psychology, University of Milan Bicocca, 20126, Milano, Italy.
Laboratory of Acute Brain Injury and Therapeutic Strategies, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milano, Italy.
J Affect Disord. 2023 Jun 1;330:300-308. doi: 10.1016/j.jad.2023.03.024. Epub 2023 Mar 17.
The SARS-CoV-2 pandemic compromised the mental health of COVID-19 patients and their family members. Due to social distancing and lockdown measures, a remote, tele-psychotherapy program for former or current COVID-19 patients and their relatives was implemented.
The primary goal of this project was to evaluate intervention feasibility. The secondary aim was to assess the impact of the intervention by means of pre-post psychological changes.
After a phone-based eligibility screening and remote neuropsychological testing, participants completed online self-reports assessing baseline COVID-related psychopathology. Next, participants attended eight tele-psychotherapy sessions. After treatment, the online self-reports were completed again.
Of 104 enrolled participants, 88 completed the intervention (84.6 % completion rate). Significant pre-post improvements were observed for generalized anxiety (d = 0.38), depression (d = 0.37), insomnia (d = 0.43), post-traumatic psychopathology (d = 0.54), and general malaise (d = 0.31). Baseline cluster analysis revealed a subgroup of 41 subjects (47.6 %) with no psychopathology, and a second subgroup of 45 subject (52.3 %) with moderate severity. Thirty-three percent of the second group reached full symptom remission, while 66 % remained symptomatic after treatment.
Remote brief tele-psychotherapy for COVID-19 patients and their first-degree relatives is feasible and preliminary efficacious at reducing COVID-related psychopathology in a subgroup of patients. Further research is needed to investigate distinct profiles of treatment response.
SARS-CoV-2 大流行损害了 COVID-19 患者及其家属的心理健康。由于采取了社交隔离和封锁措施，为前 COVID-19 患者或现 COVID-19 患者及其亲属实施了远程电话心理治疗计划。
该项目的主要目标是评估干预措施的可行性。次要目标是通过心理变化的前后评估来评估干预措施的影响。
通过电话进行资格筛选和远程神经心理测试后，参与者在线完成了评估 COVID 相关精神病理学的基线自我报告。接下来，参与者参加了八次电话心理治疗。治疗后，再次在线完成自我报告。
在 104 名入组参与者中，88 名完成了干预（84.6%的完成率）。广泛性焦虑症（d=0.38）、抑郁症（d=0.37）、失眠症（d=0.43）、创伤后精神病理学（d=0.54）和一般不适（d=0.31）方面的前后改善具有显著意义。基线聚类分析显示，41 名受试者（47.6%）没有精神病理学，45 名受试者（52.3%）为中度严重程度。第二组中的 33%达到了完全症状缓解，而 66%在治疗后仍有症状。
针对 COVID-19 患者及其一级亲属的远程简短电话心理治疗是可行的，并且在治疗组的亚组中初步显示出降低 COVID 相关精神病理学的效果。需要进一步的研究来探索不同的治疗反应特征。
