Hebei Key Laboratory of Heavy Metal Deep-Remediation in Water and Resource Reuse, Yanshan University, Qinhuangdao, 066004, PR China.
Hebei Key Laboratory of Applied Chemistry, Department of Applied Chemistry, Yanshan University, Qinhuangdao, 066004, PR China.
Anal Chim Acta. 2023 Apr 29;1252:341012. doi: 10.1016/j.aca.2023.341012. Epub 2023 Mar 3.
Heteroatom doped graphdiyne (GDY) has been demonstrated to be an effective strategy for achieving outstanding electrochemical properties, including improved electrocatalytic activity, tunable electronic properties and high electronic conductivity, by producing numerous heteroatomic defects as well as active sites. Extensive efforts have been devoted to the issue of single element doping of GDY. Introducing two or more kinds of heteroatoms into GDY materials may create a synergic effect between the co-dopants, thus generating superior electrochemical performance. Nevertheless, little research on multiple elements co-doped GDY, especially in the application of constructing electrochemical biosensor. Herein, nitrogen and fluoride co-doped GDY (N-F-GDY) has been synthesized and employed to combine with NiCoO-CoO hollow multishelled nanocages to establish an ultrasensitive electrochemical biosensor for the assay of pesticide residue. The as-prepared electrochemical biosensor possesses a wide linear range of 0.448 pM-44.8 nM for monocrotophos detection and a low detection limit of 0.0166 fM (S/N = 3).
杂原子掺杂的石墨炔（GDY）被证明是一种有效的策略，可以通过产生大量的杂原子缺陷和活性位点来实现出色的电化学性能，包括提高电催化活性、可调电子性质和高电子导电性。人们已经投入了大量的精力来研究 GDY 的单元素掺杂问题。将两种或更多种杂原子引入 GDY 材料中可能会在共掺杂剂之间产生协同效应，从而产生优异的电化学性能。然而，关于多元素共掺杂 GDY 的研究很少，特别是在构建电化学生物传感器方面的应用。本文合成了氮和氟共掺杂 GDY（N-F-GDY），并将其与 NiCoO-CoO 空心多壳层纳米笼结合，建立了一种用于检测农药残留的超灵敏电化学生物传感器。所制备的电化学生物传感器对久效磷的检测具有较宽的线性范围（0.448 pM-44.8 nM）和较低的检测限（0.0166 fM（S/N = 3））。
