Espeillac C, Charles T, Donatini G, David R, Bertheuil N, Leclère F M
Service d'urologie, CHU de Poitiers, université de Poitiers, 2, rue de la Milétrie, 86000 Poitiers, France.
Service d'urologie, CHU de Poitiers, université de Poitiers, 2, rue de la Milétrie, 86000 Poitiers, France.
Prog Urol. 2023 Apr;33(5):247-253. doi: 10.1016/j.purol.2023.02.008. Epub 2023 Mar 17.
External genitalia gangrene is a well-known uncommon disease; however, mortality remains important. Recent literature focuses on early management. The object of this study was to assess quality of life and disease-specific function, in the medium- and long-term.
We evaluated retrospectively adult inpatients with external genitalia gangrene who had a surgical debridement between 2010 and 2020 at CHU de Poitiers. Preoperatory FGSI Score was calculated for patients included. In a second phase, surviving patients at 2020 who had agreed to take part in the follow-up were assessed by clinical examination, and asked to complete Short-Form 36 test and two additional disease-specific questionnaire (USP, IIEF5).
The patients consisted of 33 men. Mean age was 61.18. Eleven patients (33%) died primarily from external genitalia gangrene. Median FGSI score was 6 (1-13). We were able to reach 11 patients (33%) for secondary clinical revaluation. Time before revaluation was 3months to 8years. All parts of SF-36 were significantly low. Mean USP score was 1.27±2.68/4.54±4.43/0.72±1.84. Nine patients (81%) suffered erectile dysfunction without any sexual intercourse possible.
Patients with external genitalia gangrene experience severe deterioration of their quality of life. Multidisciplinary healthcare process should systematically be carried out, as so as early screening of vulnerability risks factors, to improve functional outcomes and quality of life.
外生殖器坏疽是一种众所周知的罕见疾病;然而,死亡率仍然很高。近期文献聚焦于早期治疗。本研究的目的是评估中长期的生活质量和疾病特异性功能。
我们回顾性评估了2010年至2020年在普瓦捷大学中心医院接受外科清创术的外生殖器坏疽成年住院患者。为纳入的患者计算术前FGSI评分。在第二阶段,对2020年同意参与随访的存活患者进行临床检查,并要求他们完成简短健康调查问卷(Short-Form 36 test)以及另外两份疾病特异性问卷(USP、IIEF5)。
患者包括33名男性。平均年龄为61.18岁。11名患者(33%)主要死于外生殖器坏疽。FGSI评分中位数为6(1 - 13)。我们成功对11名患者(33%)进行了二次临床评估。重新评估前的时间为3个月至8年。简短健康调查问卷的所有部分得分均显著较低。USP平均评分为1.27±2.68/4.54±4.43/0.72±1.84。9名患者(81%)患有勃起功能障碍,无法进行任何性交。
外生殖器坏疽患者的生活质量严重下降。应系统地开展多学科医疗过程,以及早期筛查脆弱性风险因素,以改善功能结局和生活质量。