Department of Urology, University Hospital Waterford, Dunmore Road, Co., Waterford, X91 ER8E, Ireland.
Ir J Med Sci. 2023 Dec;192(6):3023-3027. doi: 10.1007/s11845-023-03339-0. Epub 2023 Mar 20.
Urachal remnants are a rare congenital defect resulting from failure of obliteration of a fibrous tube that connects the umbilicus to the bladder dome during embryological development. Oftentimes a urachal remnant will go undiagnosed, but occasionally a patient may present with a variety of symptoms, ultimately leading to the identification of the remnant. Given its rarity, there is very limited literature available on the management of symptomatic urachal remnants, especially in adults. Surgical resection has been the first-line management of urachal remnants for years, especially given the risk of the development of urachal adenocarcinoma secondary to recurrent infection, persistent irritation, and urinary stasis associated with some urachal remnants.
We present our experience in the management of symptomatic urachal remnants in adults at our institute and perform a brief literature review of the same.
A retrospective review of all cases who underwent surgical management of symptomatic urachal remnants between December 2015 and January 2022 was performed. Seven cases of urachal remnant excision in total were identified over the time period. Patient characteristics and perioperative parameters were analysed. Post-operative complications were measured in accordance with the Clavien-Dindo grading system.
In total, 7 cases of urachal remnants were treated at our institute over the study period. Four patients were treated with a TURBT and 3 patients were treated with a laparoscopic partial cystectomy. There were no intraoperative complications and one post-operative complication requiring readmission for intravenous antibiotics. There was one mortality but this was not as a direct result of the operative procedure. Mean length of stay was 1.71 days. Two of patients had histologically confirmed urachal adenocarcinoma and the remaining five patients had benign histology. Each patient was seen in the outpatients department 6 weeks post-operatively for clinical review and review of histology. No further follow-up was required for the patients with benign histology given resolution of symptoms and follow-up for the malignant histology was arranged appropriately following MDM.
There is a paucity of data available on the management of urachal remnants in the adult population; however, an endoscopic or laparoscopic approach is a safe and effective method of excising symptomatic urachal remnants.
脐尿管残余是一种罕见的先天性缺陷,是由于胚胎发育过程中连接脐部和膀胱穹窿的纤维管闭合失败而导致的。脐尿管残余通常未被诊断,但偶尔患者可能会出现多种症状,最终导致残余物的识别。由于其罕见性,关于症状性脐尿管残余的治疗方法,尤其是在成人中,文献非常有限。多年来,手术切除一直是脐尿管残余的一线治疗方法,尤其是考虑到一些脐尿管残余与反复感染、持续刺激和尿液淤积相关,可能会继发脐尿管腺癌。
我们介绍了我们在本院治疗成人症状性脐尿管残余的经验,并对其进行了简要的文献复习。
对 2015 年 12 月至 2022 年 1 月期间接受手术治疗的所有症状性脐尿管残余患者进行了回顾性分析。在此期间,共发现 7 例脐尿管残余切除病例。分析患者的特征和围手术期参数。根据 Clavien-Dindo 分级系统评估术后并发症。
在研究期间,我院共治疗了 7 例脐尿管残余病例。4 例患者接受 TURBT 治疗,3 例患者接受腹腔镜部分膀胱切除术治疗。无术中并发症,1 例术后并发症需住院静脉用抗生素治疗。有 1 例死亡,但这不是直接手术结果。平均住院时间为 1.71 天。2 例患者的组织学证实为脐尿管腺癌,其余 5 例患者的组织学为良性。每位患者在术后 6 周在门诊进行临床复查和组织学检查。对于组织学良性的患者,由于症状缓解,无需进一步随访;对于恶性组织学的患者,在多学科讨论后安排了适当的随访。
关于成人脐尿管残余的治疗方法,数据很少;然而,内镜或腹腔镜方法是切除症状性脐尿管残余的安全有效的方法。