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韩国自闭症谱系障碍儿童和青少年中新冠病毒病的患病率及严重程度

Prevalence and severity of COVID-19 among children and adolescents with autism spectrum disorders in the Republic of Korea.

作者信息

Yun Jieun, Kang Beomjun, Lee Jae-Ryun, Lee Hyejin, Lee Jin Yong

机构信息

Cheongju University, Republic of Korea.

Seoul National University College of Medicine, Republic of Korea.

出版信息

Autism. 2023 Nov;27(8):2397-2406. doi: 10.1177/13623613231160631. Epub 2023 Mar 19.

Abstract

It is more difficult to prevent coronavirus disease 2019 in children and adolescents with autism spectrum disorder, as they have trouble communicating and adjusting to their new daily lives like wearing masks and social distancing. However, there have not been many studies that focused on coronavirus disease 2019 among children and adolescents with autism spectrum disorder. We included all Korean citizens under the age of 19 as our study subjects. Among them, we found out the prevalence, severity, and case fatality of coronavirus disease 2019 in children and adolescents with and without autism spectrum disorder. The prevalence of coronavirus disease 2019 among children and adolescents with autism spectrum disorder was lower than that of those without autism spectrum disorder. For severity, children and adolescents with autism spectrum disorder were more likely to enter severe stages of disease and had higher hospitalization rates than those without autism spectrum disorder. There were no deaths among children and adolescents with autism spectrum disorder, while a few died among children and adolescents without autism spectrum disorder. However, due to the small number of deaths, it was difficult to determine whether there was a link between autism spectrum disorder and coronavirus disease 2019 deaths. We found that the appropriate quarantine policies have played a great role in sustaining overall low prevalence and higher hospitalization rates among children and adolescents with autism spectrum disorder than those without autism spectrum disorder. Furthermore, because Korea has fewer schools and facilities (i.e. personal care, social training, and skilled nursing facility) for children and adolescents with autism spectrum disorder than other countries, those with autism spectrum disorder have fewer social contacts than even before the COVID-19 pandemic.

摘要

在患有自闭症谱系障碍的儿童和青少年中预防2019冠状病毒病更加困难,因为他们在沟通以及适应新的日常生活(如戴口罩和保持社交距离)方面存在困难。然而,针对患有自闭症谱系障碍的儿童和青少年的2019冠状病毒病的研究并不多。我们将所有19岁以下的韩国公民纳入研究对象。在他们当中,我们查明了患有和未患有自闭症谱系障碍的儿童和青少年中2019冠状病毒病的患病率、严重程度和病死率。患有自闭症谱系障碍的儿童和青少年中2019冠状病毒病的患病率低于未患有自闭症谱系障碍的儿童和青少年。在严重程度方面,患有自闭症谱系障碍的儿童和青少年比未患有自闭症谱系障碍的儿童和青少年更易进入疾病的严重阶段,住院率也更高。患有自闭症谱系障碍的儿童和青少年中没有死亡病例,而未患有自闭症谱系障碍的儿童和青少年中有少数死亡病例。然而,由于死亡人数较少,很难确定自闭症谱系障碍与2019冠状病毒病死亡之间是否存在关联。我们发现,适当的检疫政策对于维持总体低患病率以及患有自闭症谱系障碍的儿童和青少年比未患有自闭症谱系障碍的儿童和青少年更高的住院率起到了很大作用。此外,由于韩国为患有自闭症谱系障碍的儿童和青少年提供的学校和设施(即个人护理、社会培训和专业护理机构)比其他国家少,患有自闭症谱系障碍的儿童和青少年的社交接触比新冠疫情之前甚至更少。

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