Creasey Graham
Department of Neurosurgery, Stanford University School of Medicine, & Spinal Cord Injury Service, US Department of Veterans Affairs Palo Alto Health Care System, CA, USA.
J Clin Orthop Trauma. 2023 Feb 21;39:102131. doi: 10.1016/j.jcot.2023.102131. eCollection 2023 Apr.
After damage to the spinal cord, some of the most frequent and severe complications are due to the neurogenic bladder and bowel, in spite of a variety of methods of management. Bladder and bowel emptying is usually impaired, but electrical stimulation of nerves surviving after spinal cord injury can produce controlled contraction of muscle, including the smooth muscle of the bladder and lower bowel, and this can be used to produce safe and effective bladder emptying on demand without catheters. It can also aid emptying of the bowel and reduce constipation. Hyper-reflexia of the bladder and lower bowel after spinal cord injury can produce reflex incontinence of urine and stool, and while this can sometimes be reduced by neuromodulation, it can be more predictably reduced by rhizotomy of the sacral sensory roots, while preserving the motor roots for stimulation. This combination of electrical stimulation and rhizotomy has restored bladder and bowel emptying and continence to several thousand patients, with reduced complications and improved quality of life over many years.
脊髓损伤后,尽管有多种管理方法,但一些最常见和严重的并发症是由神经源性膀胱和肠道引起的。膀胱和肠道排空通常受损,但脊髓损伤后存活神经的电刺激可使包括膀胱和下肠道平滑肌在内的肌肉产生可控收缩,这可用于按需进行安全有效的膀胱排空而无需导尿管。它还可帮助肠道排空并减少便秘。脊髓损伤后膀胱和下肠道的反射亢进可导致尿便反射性失禁,虽然有时可通过神经调节减轻,但通过切断骶部感觉神经根更可预测地减轻,同时保留运动神经根用于刺激。这种电刺激和神经根切断术的结合已使数千名患者恢复了膀胱和肠道排空及控尿功能,多年来并发症减少,生活质量得到改善。