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埃塞俄比亚南部阿尔巴门奇镇剩余药品的流行情况、处理方式及相关因素

Prevalence of leftover medicines, disposal practices, and associated factors in Arba Minch Town, Southern Ethiopia.

作者信息

Asmamaw Getahun, Agedew Tewodros, Tesfaye Besrat, Sasamo Samrawit, Gena Saude, Argeta Melkamu, Adio Aynoshe

机构信息

Department of Pharmacy, Arba Minch University, Arba Minch, Ethiopia.

出版信息

SAGE Open Med. 2023 Mar 14;11:20503121231158214. doi: 10.1177/20503121231158214. eCollection 2023.

Abstract

OBJECTIVE

The increased prevalence of leftover medicines in the community is currently a global concern due to the detrimental effects on the environment and health. However, several developing countries have failed to give sufficient consideration to the issue. The primary purpose of this study was to describe the prevalence of leftover medicines, disposal practices, and the factors affecting those in households in Arba Minch Town, Southern Ethiopia.

METHODS

A community-based, descriptive cross-sectional study was conducted among households in Bere Edigetber and Nech Sar of Arba Minch town, from June 25 to August 27, 2022. Data were gathered through face-to-face interviews with revalidated structured questionnaires. A multistage sampling technique was utilized to select each household.

RESULTS

Three hundred forty-eight households agreed to participate in a study, resulting in a 94.8% response rate. Of the study participant, 172 (49.4%) of the households had leftover medicines, with antibiotics being the most common (64% of 172). Subsidy of symptoms and saving for later use were two frequently cited reasons for the presence of leftover medicines in the house. Throwing leftover medicines in household garbage was the preferred method of disposal (>60%). Only 0.1% of respondents considered returning leftover medicines to healthcare facilities or professionals. A binary regression analysis identified four predictors for having leftover medicines. Medicines obtained without prescription were the strongest predictor (odds ratio = 3.7;  < 0.001), followed by higher family monthly income (odds ratio = 2.5;  = 0.005), those waived paying for medicine (odds ratio = 0.294;  = 0.049), and those used medications for acute diseases ( = 0.048; odds ratio = 0.450). Respondents who had prior information on safe medicine disposal were 2.3 ( = 0.04) more likely to dispose of possessed leftover medicines rather than keep them for future use.

CONCLUSIONS

This study revealed a high prevalence of leftover medicines and their improper disposal in Arba Minch town. The preferred methods of leftover medicine disposal in this study deviate from conventional standards. Significant factor variables that predict having leftover medicines are attributed to purchasing medicine without a prescription, higher family monthly income, those waived paying for medicine, and those who used medications for acute diseases. Prior knowledge of proper disposal practices predicated the decision to dispose of on-hand leftover medicines or keep them for future use. These findings would be critical in developing strategies to reduce leftover medicines and promote proper disposal practices.

摘要

目的

由于社区中剩余药品的增加对环境和健康产生不利影响,目前这已成为一个全球关注的问题。然而,一些发展中国家尚未充分考虑这一问题。本研究的主要目的是描述埃塞俄比亚南部阿尔巴明奇镇家庭中剩余药品的流行情况、处理方式以及影响这些情况的因素。

方法

2022年6月25日至8月27日,在阿尔巴明奇镇的贝雷埃迪盖特伯和内奇萨尔的家庭中开展了一项基于社区的描述性横断面研究。通过对经过重新验证的结构化问卷进行面对面访谈来收集数据。采用多阶段抽样技术选取每个家庭。

结果

348户家庭同意参与研究,回应率为94.8%。在研究参与者中,172户家庭(49.4%)有剩余药品,其中抗生素最为常见(占172户的64%)。症状缓解和留待以后使用是家庭中存在剩余药品的两个常见原因。将剩余药品扔到家庭垃圾中是首选的处理方式(>60%)。只有0.1%的受访者考虑将剩余药品返还给医疗机构或专业人员。二元回归分析确定了有剩余药品的四个预测因素。无处方获取的药品是最强的预测因素(比值比=3.7;<0.001),其次是家庭月收入较高(比值比=2.5;=0.005)、免付药费的人群(比值比=0.294;=0.049)以及使用药物治疗急性疾病的人群(=0.048;比值比=0.450)。有安全药品处理相关先验信息的受访者处理所拥有的剩余药品而非留作未来使用的可能性高2.3倍(=0.04)。

结论

本研究揭示了阿尔巴明奇镇剩余药品的高流行率及其不当处理情况。本研究中剩余药品的首选处理方式偏离了传统标准。预测有剩余药品的重要因素变量归因于无处方购买药品、家庭月收入较高、免付药费的人群以及使用药物治疗急性疾病的人群。正确处理方法的先验知识决定了是处理手头剩余药品还是留作未来使用。这些发现对于制定减少剩余药品并促进正确处理方式的策略至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b3b/10021103/7e6d7d0e68fd/10.1177_20503121231158214-fig1.jpg

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