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情绪和感觉调节障碍可能是注意力缺陷多动障碍中缺失的环节:一项综述。

Emotional and sensory dysregulation as a possible missing link in attention deficit hyperactivity disorder: A review.

作者信息

Grossman Anna, Avital Avi

机构信息

Department of Occupational Therapy, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel.

出版信息

Front Behav Neurosci. 2023 Mar 2;17:1118937. doi: 10.3389/fnbeh.2023.1118937. eCollection 2023.

Abstract

Attention Deficit Hyperactivity Disorder (ADHD) is a common developmental disorder affecting 5-7% of adults and children. We surveyed the literature to examine ADHD through three pillars: developmental characteristics, symptomatology, and treatment strategies. Firstly, in terms of developmental characterstics, early life stress may increase the risk of developing ADHD symptoms according to animal models' research. Secondly, the current core symptoms of ADHD are comprised of inattention, hyperactivity, and impulsivity. However, the up-to-date literature indicates individuals with ADHD experience emotional and sensory dysregulation as well, which early-life stress may also increase the risk of. Finally, we discuss the therapeutic benefits of methylphenidate on both the current core ADHD symptoms and the sensory and emotional dysregulation found in those with ADHD. In summation, we surveyed the recent literature to analyze (i) the potential role of early-life stress in ADHD development, (ii) the involvement of emotional and sensory dysregulation in ADHD symptomatology and finally, (iii) the therapeutic intervention with methylphenidate, aiming to reduce the potential effect of early life stress in ADHD, and mainly emotional and sensory dysregulation. The apparent but currently less recognized additional symptoms of emotional and sensory dysregulation in ADHD call for further investigation of these possible causes and thus increasing treatments efficacy in individuals with ADHD.

摘要

注意缺陷多动障碍(ADHD)是一种常见的发育障碍,影响着5%至7%的成年人和儿童。我们查阅了相关文献,从三个方面来审视ADHD:发育特征、症状学和治疗策略。首先,在发育特征方面,根据动物模型研究,早期生活压力可能会增加出现ADHD症状的风险。其次,ADHD目前的核心症状包括注意力不集中、多动和冲动。然而,最新文献表明,ADHD患者还存在情绪和感觉调节障碍,早期生活压力也可能增加这种风险。最后,我们讨论了哌甲酯对ADHD当前核心症状以及ADHD患者中发现的感觉和情绪调节障碍的治疗效果。总之,我们查阅了近期文献,以分析(i)早期生活压力在ADHD发展中的潜在作用,(ii)情绪和感觉调节障碍在ADHD症状学中的作用,以及最后(iii)哌甲酯的治疗干预,旨在减少早期生活压力对ADHD的潜在影响,主要是对情绪和感觉调节障碍的影响。ADHD中明显但目前尚未得到充分认识的情绪和感觉调节障碍的附加症状,需要对这些可能的原因进行进一步研究,从而提高ADHD患者的治疗效果。

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