Strambu Irina R
Pulmonology Department, University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania.
Institute of Pneumophthysiology "Marius Nasta", Bucharest, Romania.
Front Med (Lausanne). 2023 Mar 2;10:999066. doi: 10.3389/fmed.2023.999066. eCollection 2023.
Sarcoidosis is a multisystem granulomatosis of unknown origin, which can involve almost any organ. Most frequently the disease involves the lungs and mediastinal lymph nodes, but it can affect the skin, the eyes, nervous system, the heart, kidneys, joints, muscles, calcium metabolism, and probably any other anecdotical organ involvement. Cardiac sarcoidosis is one of the most challenging involvements, as it can lead to cardiac mortality and morbidity, and also because the diagnosis may be difficult. With no specific symptoms, cardiac sarcoidosis may be difficult to suspect in a patient with no previous extra-cardiac sarcoidosis diagnosis. This manuscript reviews the current knowledge of the diagnosis and decision to treat cardiac sarcoidosis, and illustrates the information with a case presentation of a young adult with no risk factors, no previous diagnosis of sarcoidosis, and with cardiac symptoms impairing his quality of life.
结节病是一种病因不明的多系统肉芽肿病，可累及几乎任何器官。该病最常累及肺部和纵隔淋巴结，但也可影响皮肤、眼睛、神经系统、心脏、肾脏、关节、肌肉、钙代谢，可能还会累及其他任何偶见的器官。心脏结节病是最具挑战性的累及情况之一，因为它可导致心脏死亡率和发病率升高，而且诊断可能困难。由于没有特异性症状，对于既往无心脏外结节病诊断的患者，可能很难怀疑其患有心脏结节病。本文综述了目前关于心脏结节病诊断和治疗决策的知识，并通过一例无危险因素、既往无结节病诊断且心脏症状影响其生活质量的年轻成人病例介绍来说明相关信息。
