Dinicu Andreea, Penalosa Patrick, Crosland Brian A, Steller Jonathan
University of California, Irvine, School of Medicine, Irvine, Orange, California.
Department of Obstetrics and Gynecology, University of California, Irvine, Orange, California.
AJP Rep. 2023 Mar 16;13(1):e21-e24. doi: 10.1055/a-2028-7727. eCollection 2023 Jan.
Maternal syphilis infection is a common infectious cause of nonimmune hydrops fetalis. Generally, hydrops fetalis is equated with poor prognoses in affected pregnancies. A 38-year-old G5P2114 presented at 28 weeks' gestation with newly diagnosed primary syphilis infection, sonographic findings of hydrops fetalis, and elevated middle cerebral artery Dopplers concerning for fetal anemia. Following treatment with intramuscular penicillin, the symptoms of hydrops fetalis were resolved and our patient delivered a healthy male neonate with no signs of congenital syphilis at the time of delivery. Routine and early testing for syphilis is an important component of prenatal care. Though not previously documented, the secondary findings of suspected fetal syphilis may be able to completely resolve in utero with penicillin treatment.
母亲梅毒感染是胎儿非免疫性水肿的常见感染原因。一般来说，胎儿水肿等同于受影响妊娠的预后不良。一名38岁、孕5产2（1次足月产、1次早产、1次流产、4次现存子女）的孕妇在妊娠28周时就诊，被新诊断为原发性梅毒感染，超声检查发现胎儿水肿，且大脑中动脉多普勒检查结果升高提示胎儿贫血。经肌肉注射青霉素治疗后，胎儿水肿症状得到缓解，我们的患者分娩出一名健康男婴，分娩时无先天性梅毒迹象。梅毒的常规和早期检测是产前护理的重要组成部分。虽然此前没有记录，但疑似胎儿梅毒的继发表现可能能够通过青霉素治疗在子宫内完全消退。
