ElTabbakh G H, Elejalde B R, Broekhuizen F F
Department of Obstetrics and Gynecology, University of Wisconsin Medical School, Milwaukee 53201.
J Reprod Med. 1994 May;39(5):412-4.
The incidence of congenital syphilis is on the rise. Penicillin continues to be the drug of choice for it during pregnancy. A penicillin-allergic woman with primary stage syphilis who was treated initially with erythromycin presented with fever and nonimmune fetal hydrops secondary to an intrauterine syphilitic infection. Following desensitization and penicillin therapy the fetal hydrops disappeared, the pregnancy continued to term, and the patient delivered a small-for-gestational-age but other-wise normal infant who continued to do well up to 1 year of age.
先天性梅毒的发病率正在上升。青霉素仍然是孕期治疗该病的首选药物。一名患有一期梅毒且对青霉素过敏的女性，最初接受红霉素治疗，之后因宫内梅毒感染出现发热和非免疫性胎儿水肿。在脱敏并接受青霉素治疗后，胎儿水肿消失，妊娠持续至足月，患者分娩出一名小于胎龄但其他方面正常的婴儿，该婴儿在1岁前情况良好。
