Capurro Niccolò, Herzum Astrid, Cozzani Emanuele, Burlando Martina, Riva Silvia, Paudice Michele, Parodi Aurora
Section of Dermatology, Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Dermatology Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Skin Appendage Disord. 2023 Mar;9(2):144-146. doi: 10.1159/000528804. Epub 2023 Jan 30.
Eruptive syringomas (ES) are a rare variant of syringomas, benign adnexal tumors of eccrine sweat glands' ducts. They mostly affect young-to middle-aged women, but rarely they may also occur in the elderly, requiring generally no specific treatment.
We present the case of a 76-year-old woman with sudden onset of ES. Clinical examination evidenced brown-to-orange papules and plaques on the anterior neck, corresponding dermatoscopically to orange-brownish structureless areas, with barely hinted peripheral incomplete network, superimposed on areas of light pink. Histology showed dermal proliferation of epithelial cells forming cords and ductules, confirming the clinical-dermoscopic suspect of ES. The lesions remained stable at 12-month follow-up without treatment.
This case highlights the role of dermoscopy to help differentiate ES from other clinically similar but more serious entities, such as histiocytosis, mastocytosis, and lichen planus, and to schedule the required confirmatory biopsy in due time without haste.
发疹性汗管瘤(ES)是汗管瘤的一种罕见变体,汗管瘤是一种良性的小汗腺导管附属器肿瘤。该病主要影响年轻至中年女性,但在老年人中也很少见,通常无需特殊治疗。
我们报告一例76岁女性突发发疹性汗管瘤的病例。临床检查发现其颈部前方有棕色至橙色丘疹和斑块,皮肤镜检查显示为橙棕色无结构区域,周围仅有不完整的隐约网状结构,叠加在浅粉色区域上。组织学检查显示上皮细胞在真皮层增生形成条索和小导管,证实了临床皮肤镜检查对发疹性汗管瘤的怀疑。在12个月的随访中,未经治疗的病变保持稳定。
该病例突出了皮肤镜在帮助鉴别发疹性汗管瘤与其他临床症状相似但更严重的疾病(如组织细胞增多症、肥大细胞增多症和扁平苔藓)方面的作用,并能及时安排必要的确诊活检,避免仓促行事。