Mavungu Gaël Nzuzi, Mutombo Cedrick Shakalenga, Numbi Désiré Mujike, Nsenga Salvatora Nkulu, Muyumba Welcome Nonga, Pongombo Celestin Shongo, Bakari Salvius Amuri, Nachtergael Amandine, Vandenput Sandrina, Okombe Victor Embeya, Duez Pierre
Faculty of Veterinary Medicine, Unit of Pharmacology and Therapeutic, University of Lubumbashi (UNILU), Lubumbashi, Congo.
Unit of Therapeutic Chemistry and Pharmacognosy, Université de Mons (UMONS), Mons, Belgium.
Front Pharmacol. 2023 Mar 1;14:1124267. doi: 10.3389/fphar.2023.1124267. eCollection 2023.
Gastrointestinal parasite (GIP) infections control has an important role to play in increasing livestock production from a limited natural resource base and to improve animal health and welfare. This study aimed to collect indigenous knowledge and identify wild plants locally used by goat smallholders of three territories of Haut-Katanga province for treating signs of gastrointestinal parasitism. Ethnoveterinary surveys were conducted by semi-structured interviews and a bibliographic screening of the biological activities relating to cited plants was carried out. Our interviews showed that ethnosemantic diagnoses of GIP diseases are based on signs. Eighty-seven informants reported that 27 plant species from 15 families, dominated by Fabaceae (29.6%) and Lamiaceae (18.5%) were commonly used in their goats treatment. Among these plants, five species with palmately compound leaves were considerably more used. From those, we noted a substitution of De Wild. and T. Durand (Lamiaceae) by (Welw. Ex Oliv.) J. Leonard (Picrodendraceae) and of Vatke by Oliv. Subsp. (Britten) F. White. Roots (46.9%), leaves (28.0%) and seeds (12.5%) were the most frequently used plant organs, and maceration is applied for most of the medicinal preparations (62.2%). Recipes were administered by oral route, for GIP 1) prevention (33.3%), by macerating the ground plant material in drinking water for 2 weeks at the start of each season (dry and rainy); and 2) treatment (66.7%). According to the literature, some of these plants have few or no studies investigating their anthelmintic activity. The cited plants are worth investigating further as they could constitute an effective alternative strategy in maintaining animal productivity. Studies on the biological activity of these plants can also provide indications of promising leads for extracts that could be developed into commercial standardized medications.
胃肠道寄生虫（GIP）感染控制对于在有限的自然资源基础上提高牲畜产量以及改善动物健康和福利具有重要作用。本研究旨在收集本土知识，并确定上加丹加省三个地区的山羊养殖户当地用于治疗胃肠道寄生虫症状的野生植物。通过半结构化访谈进行了民族兽医学调查，并对所引用植物的生物活性进行了文献筛选。我们的访谈表明，GIP疾病的民族语义诊断基于症状。87名受访者报告称，15个科的27种植物常用于治疗山羊，其中豆科（29.6%）和唇形科（18.5%）占主导。在这些植物中，五种具掌状复叶的植物使用更为频繁。从中我们注意到，德威特和杜兰德（唇形科）被（韦尔威. 奥利弗）J. 伦纳德（大戟科）取代，瓦特克被奥利弗亚种（布里顿）F. 怀特取代。根（46.9%）、叶（28.0%）和种子（12.5%）是最常用的植物器官，大多数药物制剂（62.2%）采用浸渍法。药方通过口服给药，用于GIP：1）预防（33.3%），在每个季节（旱季和雨季）开始时，将磨碎的植物材料在饮用水中浸渍2周；2）治疗（66.7%）。根据文献，其中一些植物很少或没有关于其驱虫活性的研究。这些被引用的植物值得进一步研究，因为它们可能构成维持动物生产力的有效替代策略。对这些植物生物活性的研究也可以为有望开发成商业标准化药物的提取物提供线索。
