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明显危及生命事件婴儿的结局。

Outcomes for the apparent life-threatening event infant.

作者信息

Dick Anne

机构信息

Canterbury Cot Death Fellowship, Department of Pediatrics, Christchurch School of Medicine University of Otago Christchurch New Zealand.

出版信息

Health Sci Rep. 2023 Mar 16;6(3):e1152. doi: 10.1002/hsr2.1152. eCollection 2023 Mar.

Abstract

AIM

To examine the outcome for apparent life-threatening event infants and the determining factors for that outcome.

METHODS

A retrospective review of 903 infants (0-12 months of age) presenting to the pediatric wards at Christchurch Hospital between 1985 and 1996 with events characterized by some combination of apnoea, change in color, and muscle tone. Events, resulting in 1088 admissions, were classified from medical record review according to the severity and underlying conditions, with risk factors and long-term outcomes examined.

RESULTS

The severity of events was reduced with implementing sudden infant death syndrome recommendations regarding the risk of prone sleeping. There were no sudden infant death syndrome deaths on home apnoea monitoring. Five apparent life-threatening event infants, not referred for home apnoea monitoring, subsequently died of sudden infant death syndrome. Two infants died and one suffered significant hypoxic insult when apnoea monitoring was interrupted under the age of 4 months. Asthma and neurodevelopmental conditions appeared to be over-represented subsequently in the apparent life-threatening event group.

CONCLUSION

Identifying apparent life-threatening event infants at risk of sudden infant death syndrome lacked specificity. The use of apnoea home monitoring appeared protective in this cohort, but safe sleeping practices remained central for reducing sudden infant death syndrome risk.

摘要

目的

研究看似危及生命事件婴儿的结局及其结局的决定因素。

方法

对1985年至1996年间在克赖斯特彻奇医院儿科病房就诊的903名(0至12个月大)婴儿进行回顾性研究,这些婴儿的事件特征为呼吸暂停、肤色改变和肌张力改变的某种组合。导致1088次入院的事件通过病历审查根据严重程度和潜在病情进行分类,并对危险因素和长期结局进行研究。

结果

随着实施关于俯卧睡眠风险的婴儿猝死综合征建议,事件的严重程度有所降低。在家中进行呼吸暂停监测期间未发生婴儿猝死综合征死亡。5名未被转诊进行家庭呼吸暂停监测的看似危及生命事件婴儿随后死于婴儿猝死综合征。2名婴儿在4个月龄前呼吸暂停监测中断时死亡,1名婴儿遭受了严重的缺氧损伤。哮喘和神经发育疾病在随后的看似危及生命事件组中似乎占比过高。

结论

识别有婴儿猝死综合征风险的看似危及生命事件婴儿缺乏特异性。在这一队列中,使用家庭呼吸暂停监测似乎具有保护作用,但安全的睡眠习惯仍然是降低婴儿猝死综合征风险的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7c3/10019060/92f486aa0c5d/HSR2-6-e1152-g001.jpg

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