Dubey Apurva, Kumar Sunil, Acharya Sourya, Nagendra Vadlamudi, Khurana Kashish
Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.
Department of Radiology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.
Cureus. 2023 Feb 14;15(2):e34968. doi: 10.7759/cureus.34968. eCollection 2023 Feb.
Hepatic encephalopathy is the most common neurologic complication of liver cirrhosis, whereas acquired hepatocerebral degeneration (AHD) is an underappreciated neurologic manifestation. Parkinsonism, ataxia, and neuropsychiatric symptoms are its defining characteristics. In individuals with chronic parenchymal liver disease with portosystemic shunting, it is an underrecognized etiology of psychomotor retardation. It has been hypothesized that the etiology of AHD is due to manganese buildup in the basal ganglia. This case report details a hepatocerebral degeneration (AHD) case in a patient with chronic parenchymal liver disease who improved after taking a dopamine agonist.
肝性脑病是肝硬化最常见的神经并发症，而获得性肝脑变性（AHD）是一种未得到充分认识的神经表现。帕金森综合征、共济失调和神经精神症状是其特征性表现。在患有慢性实质性肝病伴门体分流的个体中，它是精神运动迟缓的一种未被充分认识的病因。据推测，AHD的病因是基底节中锰的蓄积。本病例报告详细介绍了一名患有慢性实质性肝病的患者发生肝脑变性（AHD）的病例，该患者在服用多巴胺激动剂后病情有所改善。
