Ashrafzadeh Sahar, Mariano Maria Theresa, Syed Saba
David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Department of Psychiatry and Biobehavioral Sciences, Olive View-UCLA Medical Center, Sylmar, CA, USA.
Case Rep Psychiatry. 2023 Mar 8;2023:1662271. doi: 10.1155/2023/1662271. eCollection 2023.
While psychiatric manifestations are common in patients with Cushing's syndrome (CS), to our knowledge, there are no reported cases of CS presenting with functional neurological disorder (FND), a neuropsychiatric condition in which patients experience neurological symptoms, such as motor dysfunctions, sensory symptoms, speech disorders, or nonepileptic seizures, in the absence of neurological disease. Here, we report a case of a complex patient with Cushing's disease who presented with multiple FND symptoms including nonepileptic seizures, bilateral lower extremity paralysis, decreased finger flexion resulting in limited hand function, and stuttering. This case illustrates a rare psychiatric manifestation of CS presenting as multiple neurological complaints. Furthermore, we elucidate how a multidisciplinary treatment approach improved our patient's FND symptoms.
虽然精神症状在库欣综合征(CS)患者中很常见,但据我们所知,尚无CS患者出现功能性神经障碍(FND)的报道,FND是一种神经精神疾病,患者在没有神经疾病的情况下会出现神经症状,如运动功能障碍、感觉症状、言语障碍或非癫痫性发作。在此,我们报告一例患有库欣病的复杂患者,该患者出现多种FND症状,包括非癫痫性发作、双侧下肢瘫痪、手指屈曲减少导致手部功能受限以及口吃。该病例说明了CS一种罕见的精神症状表现为多种神经症状。此外,我们阐明了多学科治疗方法如何改善了我们患者的FND症状。