美国妊娠期二尖瓣狭窄的住院情况：一项为期13年的分析。
Hospital admissions for mitral stenosis in pregnancy in the United States: a thirteen-year analysis.
作者信息
Lima Neiberg de Alcantara, Patel Dhruvil Ashishkumar, Sundaram Nikhil, de Castro Ricardo Lessa, Huffman Cuyler, Diaz Mireya, Linares Silvia Teresa, Melgar Thomas A
机构信息
Division of Cardiology, Department of Internal Medicine-Wayne State University Detroit 48201, Michigan, USA.
Wayne State University School of Medicine Detroit 48201, Michigan, USA.
出版信息
Am J Cardiovasc Dis. 2023 Feb 15;13(1):10-20. eCollection 2023.
BACKGROUND
Cardiac conditions are a significant cause of maternal morbidity and mortality, significantly exacerbated during the hemodynamic demands of pregnancy. Mitral stenosis in pregnancy (MSp) is rare in the USA however, it has a high risk for maternal complications.
METHODS
We aim to outline the burden of MSp hospitalizations nationally. A retrospective review of HCUP/NIS data from 2002-2014 was conducted.
RESULTS
There were 2014 weighted discharges for both pregnancy and mitral stenosis (MS). Patients diagnosed with MS had a more considerable mean cost per discharge than the comparison group. Pulmonary Hypertension (PH), Atrial Arrhythmias (AA), Stroke, and Heart Failure (HF) were respectively reported in 25.71%, 7.14%, 0.95%, and 19.28% of the discharges. Our study identified a low incidence of MS in the US over the 12-year period; no deaths were identified.
CONCLUSION
Our results substantiate MSp as a risk factor for PH, AA, HF, and stroke in pregnancy. Even though the mortality is low, it is essential that clinicians be aware of this diagnosis due to higher associated morbidity and costs.
背景
心脏疾病是孕产妇发病和死亡的重要原因，在孕期血流动力学需求增加时会显著加剧。孕期二尖瓣狭窄（MSp）在美国较为罕见，但其孕产妇并发症风险较高。
方法
我们旨在概述全国范围内MSp住院治疗的负担。对2002年至2014年的医疗成本和利用项目/国家住院样本（HCUP/NIS）数据进行了回顾性分析。
结果
共有2014例妊娠合并二尖瓣狭窄（MS）的加权出院病例。诊断为MS的患者每次出院的平均费用比对照组更高。分别有25.71%、7.14%、0.95%和19.28%的出院病例报告有肺动脉高压（PH）、房性心律失常（AA）、中风和心力衰竭（HF）。我们的研究发现，在这12年期间美国MS的发病率较低；未发现死亡病例。
结论
我们的结果证实MSp是孕期发生PH、AA、HF和中风的一个危险因素。尽管死亡率较低，但由于相关发病率和成本较高，临床医生必须了解这一诊断。
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