Department of Surgery, Oregon Health and Science University, Oregon, Portland, USA.
Nutr Clin Pract. 2023 Jun;38(3):557-563. doi: 10.1002/ncp.10973. Epub 2023 Mar 20.
Chyle leaks of any source or type can cause significant morbidity and mortality. Attention to the anatomy and physiology of the leak, followed by stepwise dietary and pharmacologic management, obviates the need for surgical intervention in a majority of patients. In this article, we review the importance, etiology, anatomy, diagnosis, nutrition and immunologic effects, and options for treatment of chylothorax and chylous ascites based on experience and prior literature. We propose a multidisciplinary approach to optimize these treatments including the primary surgical teams, pharmacists, and dietitians, with reoperation as a last resort to minimize the morbidity of this challenging complication.
任何来源或类型的乳糜漏都可能导致严重的发病率和死亡率。关注漏出的解剖和生理学,然后逐步进行饮食和药物管理,可以避免大多数患者需要手术干预。本文根据经验和既往文献,回顾乳糜胸和乳糜性腹水的重要性、病因、解剖、诊断、营养和免疫影响以及治疗选择。我们提出了一种多学科方法来优化这些治疗方法,包括主要的手术团队、药剂师和营养师,将再次手术作为最后的手段,以尽量减少这种具有挑战性的并发症的发病率。