Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.
Institute of HIV Research and Innovation, Bangkok, Thailand.
Trop Med Int Health. 2023 May;28(5):374-383. doi: 10.1111/tmi.13872. Epub 2023 Mar 31.
First, to describe the antiretroviral therapy (ART) delivery models available in Thailand to understand differentiated service delivery for further service system optimization and expansion of best practices; second, to determine the client characteristics associated with model uptake.
Across-sectional assessment using secondary data was conducted to describe ART models implemented as routine services at four public hospitals in three major provinces with a high-HIV burden in Thailand. From April to October 2020, ART clients were screened consecutively according to the inclusion criteria: Thai, aged ≥18 years, and on ART for ≥6 months. HIV treatment models were categorised based on the service type, location, provider, and frequency. Logistic regression was used to identify the associated factors.
Seven individual ART delivery models were identified: four were facility-based and three were out-of-facility. No group models were identified. Of 3,366 records of ART clients reviewed, 3,213 (95.5%) met the study criteria and received ART through the following models: conventional (32.6%), nurse-led clinical consultation (10.0%), fast-track refill (29.0%), after-hours clinic (10.6%), pharmacist-led pickup center (3.6%), key population-led community-based organisation (2.7%), and mailing (11.5%). Age, population, duration on ART, and viral load were associated with the uptake of certain alternative service models when compared to the conventional model.
Among the variety of ART delivery approaches available in Thailand, facility-based models remain the most prevalent. Future work should investigate the role of client preference and choice in choosing service models and service utilisation patterns over time, and assess the acceptability and effectiveness of these models.
首先,描述泰国现有的抗逆转录病毒疗法(ART)提供模式,以了解差异化服务提供,进一步优化服务系统并扩大最佳实践;其次,确定与模式采用相关的客户特征。
本研究采用横断面评估,利用泰国 3 个艾滋病高发大省的 4 家公立医院的二级数据,描述作为常规服务提供的 ART 模式。2020 年 4 月至 10 月,按照纳入标准连续筛选接受 ART 治疗≥6 个月的泰国籍、年龄≥18 岁的 ART 患者:服务类型、地点、提供者和频率对 HIV 治疗模式进行分类。采用逻辑回归确定相关因素。
确定了 7 种个体 ART 提供模式:4 种是基于机构的,3 种是机构外的。未发现团体模式。在审查的 3366 份 ART 患者记录中,3213 份(95.5%)符合研究标准,通过以下模式接受 ART:常规(32.6%)、护士主导的临床咨询(10.0%)、快速配药(29.0%)、夜间门诊(10.6%)、药剂师主导的取药中心(3.6%)、重点人群主导的社区组织(2.7%)和邮寄(11.5%)。与常规模式相比,年龄、人群、ART 持续时间和病毒载量与某些替代服务模式的采用相关。
在泰国提供的各种 ART 提供方法中,基于机构的模式仍然最为普遍。未来的工作应研究患者偏好和选择在选择服务模式和服务利用模式方面的作用,以及评估这些模式的可接受性和有效性。