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评价泰国曼谷将远程医疗融入同日启动抗逆转录病毒治疗服务中的情况,以应对 COVID-19:基于真实世界数据的混合方法分析。

Evaluation of the integration of telehealth into the same-day antiretroviral therapy initiation service in Bangkok, Thailand in response to COVID-19: a mixed-method analysis of real-world data.

机构信息

Institute of HIV Research and Innovation, Bangkok, Thailand.

Department of Epidemiology, Columbia University Mailman School of Public Health, New York, USA.

出版信息

J Int AIDS Soc. 2021 Oct;24 Suppl 6(Suppl 6):e25816. doi: 10.1002/jia2.25816.

Abstract

INTRODUCTION

Same-day antiretroviral therapy (SDART) initiation has been implemented at the Thai Red Cross Anonymous Clinic (TRCAC) in Bangkok, Thailand, since 2017. HIV-positive, antiretroviral therapy (ART)-naïve clients who are willing and clinically eligible start ART on the day of HIV diagnosis. In response to the first wave of the coronavirus disease 2019 (COVID-19) outbreak in March 2020, telehealth follow-up was established to comply with COVID-19 preventive measures and allow service continuation. Here, we evaluate its implementation.

METHODS

Pre-COVID-19 (until February 2020) clients who initiated SDART received a 2-week ART supply and returned to the clinic for evaluation before being referred to long-term ART maintenance facilities. If no adverse events (AEs) occurred, another 8-week ART supply was provided while referral was arranged. During the first wave of COVID-19 (March-May 2020), clients received a 4-week ART supply and the option of conducting follow-up consultation and physical examination via video call. Clients with severe AEs were required to return to TRCAC; those without received another 6-week ART supply by courier to bridge transition to long-term facilities. This adaptation continued post-first wave (May-August 2020). Routine service data were analysed using data from March to August 2019 for the pre-COVID-19 period. Interviews and thematic analysis were conducted to understand experiences of clients and providers, and gain feedback for service improvement.

RESULTS

Of 922, 183 and 321 eligible clients from the three periods, SDART reach [89.9%, 96.2% and 92.2% (p = 0.018)] and ART initiation rates [88.1%, 90.9% and 94.9% (p<0.001)] were high. ART uptake, time to ART initiation and rates of follow-up completion improved over time. After the integration, 35.3% received the telehealth follow-up. The rates of successful referral to a long-term facility (91.8% vs. 95.3%, p = 0.535) and retention in care at months 3 (97.5% vs. 98.0%, p = 0.963) and 6 (94.1% vs. 98.4%, p = 0.148) were comparable for those receiving in-person and telehealth follow-up. Six clients and nine providers were interviewed; six themes on service experience and feedback were identified.

CONCLUSIONS

Telehealth follow-up with ART delivery for SDART clients is a feasible option to differentiate ART initiation services at TRCAC, which led to its incorporation into routine service.

摘要

简介

自 2017 年以来,泰国曼谷的泰国红十字会匿名诊所(TRCAC)已实施同日抗逆转录病毒疗法(SDART)。愿意且符合临床条件的 HIV 阳性、抗逆转录病毒治疗(ART)初治患者在 HIV 诊断当天开始接受 ART。为应对 2020 年 3 月首次爆发的 2019 年冠状病毒病(COVID-19),建立了远程医疗随访以遵守 COVID-19 预防措施并允许继续提供服务。在此,我们评估其实施情况。

方法

在 COVID-19 之前(截至 2020 年 2 月)开始 SDART 的患者接受 2 周的 ART 供应,并在转介到长期 ART 维持设施之前返回诊所进行评估。如果没有不良事件(AE)发生,则在安排转介的同时再提供 8 周的 ART 供应。在 COVID-19 第一波(2020 年 3 月至 5 月)期间,患者接受了 4 周的 ART 供应,并可选择通过视频通话进行随访咨询和体检。出现严重 AE 的患者需要返回 TRCAC;没有 AE 的患者则通过快递获得另外 6 周的 ART 供应,以过渡到长期设施。这种适应在第一波之后继续进行(2020 年 5 月至 8 月)。使用 2019 年 3 月至 8 月的数据对 COVID-19 前期间的常规服务数据进行分析。进行了访谈和主题分析,以了解患者和提供者的经验,并为服务改进提供反馈。

结果

在三个时期中,有 922、183 和 321 名符合条件的患者,SDART 覆盖率[89.9%、96.2%和 92.2%(p = 0.018)]和 ART 启动率[88.1%、90.9%和 94.9%(p<0.001)]均很高。ART 使用率、开始 ART 的时间和随访完成率随时间推移而提高。整合后,有 35.3%的患者接受了远程医疗随访。成功转介到长期机构的比例(91.8%对 95.3%,p = 0.535)和在第 3 个月(97.5%对 98.0%,p = 0.963)和第 6 个月(94.1%对 98.4%,p = 0.148)的保留率在接受现场和远程医疗随访的患者中是可比的。对 6 名患者和 9 名提供者进行了访谈;确定了关于服务经验和反馈的 6 个主题。

结论

对 SDART 患者进行 ART 输送的远程医疗随访是区分 TRCAC 中 ART 启动服务的可行选择,这使其纳入了常规服务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e85/8554221/ac8b6a5b1ca0/JIA2-24-e25816-g002.jpg

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