Department of Paediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway.
The Faculty of Health and Social Sciences, Western Norway University of Applied Sciences, Bergen, Norway.
Acta Paediatr. 2023 Jun;112(6):1220-1225. doi: 10.1111/apa.16759. Epub 2023 Mar 28.
The aim of this study was to investigate psychometric properties, reliability and validity, of Astrid Lindgren and Lund Children's Hospitals Pain and Stress Assessment Scale for Preterm and Sick Newborn Infants (ALPS-Neo), as a measure for procedural pain.
This observational, prospective study with a repeated measures design, explored inter-rater reliability by two raters assessing 21 neonates during non-pain and pain events. Construct validity was explored, that is, ability to discriminate between non-pain and pain, and criterion validity by correlating ALPS-Neo with Premature Infant Pain Profile-Revised (PIPP-R) and Skin Conductance Algesimeter (SCA) in 54 neonates without ventilator support and sedation undergoing routine heel-stick procedure in a tertiary neonatal intensive care unit.
Mean gestational and assessment age of 54 infants was 33.8 weeks and 12.7 days respectively. Inter-rater reliability from baseline, skin wiping, heel-stick events for 21 infants demonstrated intraclass correlations with 95% confidence intervals (CI) of 0.49 (-0.27 to 0.79), 0.86 (0.65-0.94) and 0.73 (0.34-0.89) respectively. ALPS-Neo discriminated significantly between baseline, non-pain and heel-stick (mean differences from pain event -2.3 and -1.0 respectively) and correlated during heel-stick with PIPP-R (r = 0.56, 95% CI: 0.34-0.72), not with SCA.
ALPS-Neo may be used as a measure for procedural pain.
本研究旨在探讨 Astrid Lindgren 和 Lund 儿童医院早产儿和患病新生儿疼痛与应激评估量表(ALPS-Neo)作为一种程序性疼痛测量工具的心理测量学特性、信度和效度。
本观察性前瞻性研究采用重复测量设计,通过两位评估者在非疼痛和疼痛事件期间对 21 名新生儿进行评估,以探索组内信度。通过在 54 名无呼吸机支持和镇静的新生儿中进行常规足跟采血过程,并与早产儿疼痛评估修订版(PIPP-R)和皮肤电导率痛觉计(SCA)进行相关性分析,以探索结构效度,即区分非疼痛和疼痛的能力以及标准效度。
54 名婴儿的平均胎龄和评估年龄分别为 33.8 周和 12.7 天。21 名婴儿的基线、皮肤擦拭、足跟采血事件的组内信度的组内相关系数(95%置信区间)分别为 0.49(-0.27 至 0.79)、0.86(0.65-0.94)和 0.73(0.34-0.89)。ALPS-Neo 能显著区分基线、非疼痛和足跟采血(疼痛事件的平均差值分别为-2.3 和-1.0),并在足跟采血时与 PIPP-R 呈正相关(r=0.56,95%CI:0.34-0.72),与 SCA 无相关性。
ALPS-Neo 可作为一种程序性疼痛测量工具。